Neuroprotective effect of Metformin onReserpine induced model of Parkinsonismin rats / (Record no. 73131)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02658cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223032336.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 190728s2018 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.11.29.M.Sc.2018.Mo.N |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Monica Gamal Fawzy |
| 245 10 - TITLE STATEMENT | |
| Title | Neuroprotective effect of Metformin onReserpine induced model of Parkinsonismin rats / |
| Statement of responsibility, etc. | Monica Gamal Fawzy ; Supervised Ghada Mohamed Abdelzher Hashem , Ghada Farouk Saleh , Walaa Ibrahim Ali |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | الدورالوقائى العصبى للميتفورمين على الشلل الرعاش المحدث فى الجرذان بواسطة الريزيربين |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Monica Gamal Fawzy , |
| Date of publication, distribution, etc. | 2018 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 122 P. : |
| Other physical details | charts , facsimiles ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pharmacology |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Introduction: This is an experimental comparative study of the neuroprotective effects of metformin (low dose 100 mg/kg and high dose 250 mg/kg) and selegiline (0.25 mg/kg) in Parkinson disease induced in rats by Reserpine (0.1 mg/kg). Materials and methods: 56 healthy adult male rats weighing 150 - 200 gm were used and divided into 7 groups (8 rats each). Group 1 (Normal control group): Animals were injected with normal saline. Group 2 (Reserpine group). Group 3 (Low dose Metformin + Reserpine group). Group 4 (High dose Metformin + Reserpine group). Group 5 (Selegiline + Reserpine group). Group 6 (Low dose Metformin + Selegiline + Reserpine group). Group 7 (High dose Metformin + Selegiline + Reserpine group).All drugs were started from day 1 and continued for 21 days.To detect behavioural changes; Morris water maze,hang wire and forced swim tests were done to detect memory changes, motor assessment and estimation of depression respectively. The tests were done on days 1, 11 and 21. At the end of the experiment, serum blood samples were obtained to assess serum blood glucose, then rats were sacrificed and their brains were dissected and homogenized to measure dopamine, Ü synuclein and oxidative stress markers; malondialdehyde (MDA) and reduced glutathione (GSH) levels |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Metformin |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Parkinson |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Reserpine |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ghada Farouk Saleh , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ghada Mohamed Abdelzher Hashem , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Walaa Ibrahim Ali , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Shimaa |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.11.29.M.Sc.2018.Mo.N | 01010110078822000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.11.29.M.Sc.2018.Mo.N | 01020110078822000 | 22.09.2023 | CD - Rom | 78822.CD |