Evaluation of the therapeutic effects of formulated curcumin nanoparticles in an animal model of depression / (Record no. 73408)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02601nam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223032344.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 190820s2019 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | Ph.D |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.12.04.Ph.D.2019.Ha.E |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Hanaa Mohamed Amer Zaki Abdelaal |
| 245 10 - TITLE STATEMENT | |
| Title | Evaluation of the therapeutic effects of formulated curcumin nanoparticles in an animal model of depression / |
| Statement of responsibility, etc. | Hanaa Mohamed Amer Zaki Abdelaal ; Supervised Haitham Sharaf Eldin Mohammed , Tharwat Mahmoud Elsherbini , Yasser Ashry Khadrawy |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | تقييم التأثيرات العلاجية لجزئيات النانوكوركومين المصنعة فى نموذج حيوانى لمرض الاكتئاب |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Hanaa Mohamed Amer Zaki Abdelaal , |
| Date of publication, distribution, etc. | 2019 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 85 P. : |
| Other physical details | charts , facsimiles ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (Ph.D.) - Cairo University - Faculty of Science - Department of Biophysics |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | The objective of this study was to formulate curcumin nanoparticles (CNPs) using different techniques such as wet milling, ultrasonic homogenization and freeze drying. The resulted CNPs particles was 75 nm in average. The potential efficiency of CNPs as a treatment agent for depression has been tested against the oxidative stress, monoamines depletion, changes in active phase in FST and changes in ECoG induced by reserpine. Each one of these tests have been conducted for two-time intervals 7 days and 15 days in both cortex and hippocampus of male rats brains in an experimental animal model of depression. Results shows that the 15 days of treatment were more efficient than the 7 days treatment in both cortex and hippocampus. As it restores the monoamines neurotransmitters depletion, recovers the values of MDA, NO and GSH and restores the spectral band power of the ECoG waves to control-like values. Moreover, it succeeded to restore the duration of active phase in FST to control-like values. As a Conclusion the CNPs have both antioxidant and antidepressant properties more efficient than native form of curcumin |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Curcumin nanoparticles (CNPs) |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | ECoG |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Oxidative stress |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Haitham Sharaf Eldin Mohammed , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Tharwat Mahmoud Elsherbini , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Yasser Ashry Khadrawy , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Shimaa |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.12.04.Ph.D.2019.Ha.E | 01010110079090000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.12.04.Ph.D.2019.Ha.E | 01020110079090000 | 22.09.2023 | CD - Rom | 79090.CD |