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Study on the potential antimicrobial activities of Melaleuca spp. plant against skin infecting microbes and detection of their possible mutagenic effect using molecular methods / (Record no. 73418)

MARC details
000 -LEADER
fixed length control field 03032cam a2200349 a 4500
003 - CONTROL NUMBER IDENTIFIER
control field EG-GiCUC
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20250223032344.0
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 190920s2019 ua dh f m 000 0 eng d
040 ## - CATALOGING SOURCE
Original cataloging agency EG-GiCUC
Language of cataloging eng
Transcribing agency EG-GiCUC
041 0# - LANGUAGE CODE
Language code of text/sound track or separate title eng
049 ## - LOCAL HOLDINGS (OCLC)
Holding library Deposite
097 ## - Thesis Degree
Thesis Level Ph.D
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC)
Classification number Cai01.08.06.Ph.D.2019.As.S
100 0# - MAIN ENTRY--PERSONAL NAME
Personal name Ashraf Osman Abdellatif Mohamed
245 10 - TITLE STATEMENT
Title Study on the potential antimicrobial activities of Melaleuca spp. plant against skin infecting microbes and detection of their possible mutagenic effect using molecular methods /
Statement of responsibility, etc. Ashraf Osman Abdellatif Mohamed ; Supervised Mohammed A. M. Ramadan , Alaa Eldein M. S. Hosny , Mohamed Abdelaaty M. Rabeh
246 15 - VARYING FORM OF TITLE
Title proper/short title دراسة علي الفاعلية المحتملة لنبات الميلالوكا ضد الميكروبات المُعدِية للجلد والكشف عن التأثير المحتمل لإحداث طفرات باستخدام طرق جزيئية
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Place of publication, distribution, etc. Cairo :
Name of publisher, distributor, etc. Ashraf Osman Abdellatif Mohamed ,
Date of publication, distribution, etc. 2019
300 ## - PHYSICAL DESCRIPTION
Extent 162 P. :
Other physical details charts , facsimiles ;
Dimensions 25cm
502 ## - DISSERTATION NOTE
Dissertation note Thesis (Ph.D.) - Cairo University - Faculty of Pharmacy - Department of Microbiology and Immunology
520 ## - SUMMARY, ETC.
Summary, etc. Introduction: The extracts and oils from Melaleuca spp.leaves (Myrtaceae family) have been traditionally used as a topical therapeutic agent for the treatment of various skin infections. The current study aimed to evaluate the potential antimicrobial activities of the different active components of Melaleuca spp. plant as topical agents against some medically important pathogens related to the common skin infections and detection of their possible mutagenic effect. Methods: The M. alternifolia leaves were subjected to successive fractionation using different solvents with different polarities.The TTOwas extractedfrom plant leaves using steam hydro-distillation andthen subjected to GC/MS analysis to characterize its main components. The aqueous extract fraction was used to synthesize silver nanoparticles (AgNPs) via green nanotechnology. The different extracted fractions, TTO, and AgNPs were evaluated for their antimicrobial activities against representativeskin-infecting pathogen including bacteria, fungi and viruses.Furthermore, theTransmission electron microscope examination was used to characterize the synthesized AgNPs and to visualize the treated microbial cells to figure out the basic changes that may be referred to a certain mode of action.Moreover, the possible mutagenic effect of TTO and AgNPs was investigated against S. typhimurium TA89 and TA100 strains using the Ames test
530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE
Additional physical form available note Issued also as CD
653 #4 - INDEX TERM--UNCONTROLLED
Uncontrolled term GC/MS
653 #4 - INDEX TERM--UNCONTROLLED
Uncontrolled term Silver nanoparticles
653 #4 - INDEX TERM--UNCONTROLLED
Uncontrolled term Tea tree oil
700 0# - ADDED ENTRY--PERSONAL NAME
Personal name Alaa Eldein M. S. Hosny ,
Relator term
700 0# - ADDED ENTRY--PERSONAL NAME
Personal name Mohamed Abdelaaty M. Rabeh ,
Relator term
700 0# - ADDED ENTRY--PERSONAL NAME
Personal name Mohammed A. M. Ramadan ,
Relator term
856 ## - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a>
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN)
Cataloger Nazla
Reviser Revisor
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN)
Cataloger Shimaa
Reviser Cataloger
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme Dewey Decimal Classification
Koha item type Thesis
Holdings
Source of classification or shelving scheme Not for loan Home library Current library Date acquired Full call number Barcode Date last seen Koha item type Copy number
Dewey Decimal Classification   المكتبة المركزبة الجديدة - جامعة القاهرة قاعة الرسائل الجامعية - الدور الاول 11.02.2024 Cai01.08.06.Ph.D.2019.As.S 01010110079098000 22.09.2023 Thesis  
Dewey Decimal Classification   المكتبة المركزبة الجديدة - جامعة القاهرة مخـــزن الرســائل الجـــامعية - البدروم 11.02.2024 Cai01.08.06.Ph.D.2019.As.S 01020110079098000 22.09.2023 CD - Rom 79098.CD