Synthesis of some New pyrazolo[1,5-a]pyrimidine derivatives with expected biological activity / (Record no. 73532)
[ view plain ]
| 000 -LEADER | |
|---|---|
| fixed length control field | 02450cam a2200337 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223032348.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 190828s2019 ua f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.12.10.M.Sc.2019.Ah.S |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Ahmed Sabri Abdelmoety Gabr |
| 245 10 - TITLE STATEMENT | |
| Title | Synthesis of some New pyrazolo[1,5-a]pyrimidine derivatives with expected biological activity / |
| Statement of responsibility, etc. | Ahmed Sabri Abdelmoety Gabr ; Supervised Hussein Fouad Zohdi , Nadia Hanafy Metwally |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | 1,5-aتشييد بعض مشتقات البيرازولو يريميدين الجديدة و المتوقع لها نشاط بيولوجى |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Ahmed Sabri Abdelmoety Gabr , |
| Date of publication, distribution, etc. | 2019 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 100 P. ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (M.Sc.) - Cairo University - Faculty of Science - Department of Organic Chemistry |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | The condensation of 2-(cyanomethyl)-7-(thiophen-2-yl)-5-(trifluoromethyl)pyrazolo- [1,5-a]pyrimidine-3-carbonitrile (3) with various aromatic aldehydes afforded crossponding substituted pyrazolo[1,5-a]pyrimidines 5a-j. The reaction of compound 3 with aryl diazonium chlorides in N,N-dimethylformamide furnished arylhydrazo compounds based pyrazolo[1,5-a]pyrimidine derivative. Also, reaction of compound 3 with 4-aryl azosalicylaldehydes afforded polyheterocyclic compounds based pyrazolo[1,5-a]pyrimidine derivative. The treatment of compound 3 with phenyl isothiocyanate, followed by addition of -haloesters or haloketones afforded polyheterocyclic compounds. Moreover, the enamines compound 3 react with each of hydrazine hydrate, guanidine hydrochloride to give the pyrazolo and pyrimidine derivatives. The structures of all the newly synthesized products were established by their elemental analyses, spectral data and possible mechanism has been postulated to account for their formation. The antiviral activity of some selected newly synthesized compounds was investigated |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | 2-(cyanomethyl)-7-(thiophen-2-yl)-5-(trifluoromethyl)pyrazolo- [1,5-a] |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Polyfused heterocyclic compounds |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | pyrimidine-3-carbonitrile |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Hussein Fouad Zohdi , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Nadia Hanafy Metwally , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Samia |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.12.10.M.Sc.2019.Ah.S | 01010110078963000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.12.10.M.Sc.2019.Ah.S | 01020110078963000 | 22.09.2023 | CD - Rom | 78963.CD |