Prevalence and prognostic implication Of BCR/ABL fusion gene expression & JAK2 overexpression In Egyptian acute myeloid leukemia patients / (Record no. 73753)
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000 -LEADER | |
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fixed length control field | 02613cam a2200349 a 4500 |
003 - CONTROL NUMBER IDENTIFIER | |
control field | EG-GiCUC |
005 - DATE AND TIME OF LATEST TRANSACTION | |
control field | 20250223032354.0 |
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
fixed length control field | 190909s2019 ua dh f m 000 0 eng d |
040 ## - CATALOGING SOURCE | |
Original cataloging agency | EG-GiCUC |
Language of cataloging | eng |
Transcribing agency | EG-GiCUC |
041 0# - LANGUAGE CODE | |
Language code of text/sound track or separate title | eng |
049 ## - LOCAL HOLDINGS (OCLC) | |
Holding library | Deposite |
097 ## - Thesis Degree | |
Thesis Level | Ph.D |
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
Classification number | Cai01.19.03.Ph.D.2019.La.P |
100 0# - MAIN ENTRY--PERSONAL NAME | |
Personal name | Lamiaa Abdelfattah Fathalla Ahmed |
245 10 - TITLE STATEMENT | |
Title | Prevalence and prognostic implication Of BCR/ABL fusion gene expression & JAK2 overexpression In Egyptian acute myeloid leukemia patients / |
Statement of responsibility, etc. | Lamiaa Abdelfattah Fathalla Ahmed ; Supervised Basma Mostafa Mohammed Elgamal , Naglaa Mostafa Hassan Ahmed , Omnia Kamal Elgebaly |
246 15 - VARYING FORM OF TITLE | |
Title proper/short title | فى مرض سرطان الدم الميلودى الحاد فى المصريين و علاقتهم بالتنبؤ المرضى لديهم JAK2 و زيادة تعبير ال BCR/ABL دراسة نسبة انتشار جين ال |
260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
Place of publication, distribution, etc. | Cairo : |
Name of publisher, distributor, etc. | Lamiaa Abdelfattah Fathalla Ahmed , |
Date of publication, distribution, etc. | 2019 |
300 ## - PHYSICAL DESCRIPTION | |
Extent | 157 P. : |
Other physical details | charts , facsimiles ; |
Dimensions | 25cm |
502 ## - DISSERTATION NOTE | |
Dissertation note | Thesis (Ph.D.) - Cairo University - National Cancer Institute - Department of Clinical Pathology |
520 ## - SUMMARY, ETC. | |
Summary, etc. | Background: Acute myeloid leukemia (AML) is a heterogenous disease with multiple established prognostic factors. JAK2 overexpression in AML was confirmed by many authors with an influence on the overall survival. Philadelphia positive AML (Ph+ AML) is a provisional entity in the recent WHO classification where discrimination from acute blastic crisis on top of chronic myeloid leukemia (CML) is still a challenge. Aims: to study JAK2 gene expression pattern in AML patients and its relation with other established prognostic variables and outcome parameters. Also, to determine the prevalence of the BCR-ABL fusion gene in AML cases with determination of the clinical and laboratory criteria of these cases. Methods: Prospective study on 175 AML patients treated at medical and pediatric oncology departments. Jak2 gene expression was evaluated by real time RT-PCR using taqman primer probe assay and BCR/ABL fusion was tested by conventional RT-PCR. All patients received current standard of care treatment for AML at NCI, Cairo University, Egypt |
530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
Additional physical form available note | Issued also as CD |
653 #4 - INDEX TERM--UNCONTROLLED | |
Uncontrolled term | BCR/ABL |
653 #4 - INDEX TERM--UNCONTROLLED | |
Uncontrolled term | JAK2 |
653 #4 - INDEX TERM--UNCONTROLLED | |
Uncontrolled term | Ph+ AML |
700 0# - ADDED ENTRY--PERSONAL NAME | |
Personal name | Basma Mostafa Mohammed Elgamal , |
Relator term | |
700 0# - ADDED ENTRY--PERSONAL NAME | |
Personal name | Naglaa Mostafa Hassan Ahmed , |
Relator term | |
700 0# - ADDED ENTRY--PERSONAL NAME | |
Personal name | Omnia Kamal Elgebaly , |
Relator term | |
856 ## - ELECTRONIC LOCATION AND ACCESS | |
Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
Cataloger | Nazla |
Reviser | Revisor |
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
Cataloger | Shimaa |
Reviser | Cataloger |
942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
Source of classification or shelving scheme | Dewey Decimal Classification |
Koha item type | Thesis |
Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
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Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.19.03.Ph.D.2019.La.P | 01010110079188000 | 22.09.2023 | Thesis | ||
Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.19.03.Ph.D.2019.La.P | 01020110079188000 | 22.09.2023 | CD - Rom | 79188.CD |