A Study on the potential synergistic combination of Ý-lactam antibiotics with metallic nanoparticles against multi-drug resistant bacteria / (Record no. 73857)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02907cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223032357.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 190914s2019 ua d f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.08.06.M.Sc.2019.No.S |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Noha Mohamed Taha Mohamed Abbas |
| 245 12 - TITLE STATEMENT | |
| Title | A Study on the potential synergistic combination of Ý-lactam antibiotics with metallic nanoparticles against multi-drug resistant bacteria / |
| Statement of responsibility, etc. | Noha Mohamed Taha Mohamed Abbas ; Supervised Mohammed Abdelhaleem Ramadan , Yasser Elmohammadi Ragab , Walaa Said Mohamed Abdelaal |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | دراسة مدى الفاعلية المحتملة لاتحاد البيتالاكتام مع الجزيئات النانومترية للمعادن ضد البكتريا المتعددة المقاومة للمضادات الحيوية |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Noha Mohamed Taha Mohamed Abbas , |
| Date of publication, distribution, etc. | 2019 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 197 P. : |
| Other physical details | charts ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Microbiology and Immunology |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | The emergence of bacterial resistance against antibiotics happened due to the misuse of them, so the aim of the study was to discover a new strategy to solve the problem, such as a novel antimicrobial nano-composite with greater. For this purpose, a total of 48 isolates were collected from Elkasr Elainy hospital and identified as Staphylococcus aureus, Pseudomonas aeruginosa and Klebseilla pneumoniae, antibiotic susceptibility was carried out, ampicillin and cefalexin were selected for conjugation with silver nanoparticles as the majority of isolates showed resistance against them, and silver nano particles were prepared by the chemical reduction method. Then, silver nanoparticles were functionalized with ampicillin and cefalexin, Transmission Electron Microscopy, UV spectroscopy, zetasizer and Fourier transform infrared spectroscopy were used for characterization before and after conjugation with antibiotics, thier antibacterial activity alone, and after combination with antibiotics were determined. The data showed that antibiotic{u2013} silver nano conjugateincreased the bactericidal efficacy of antibiotics to 30 {u2013}to 100 fold higher than the antibiotics alone, In addition, invivo study showed efficient results of antibiotic-silver nano conjugated formula for wound healing, compared to dermazin cream |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Multi-drug |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Nanoparticles |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Ý-lactam |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mohammed Abdelhaleem Ramadan , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Walaa Said Mohamed Abdelaal , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Yasser Elmohammadi Ragab , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Shimaa |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.08.06.M.Sc.2019.No.S | 01010110079288000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.08.06.M.Sc.2019.No.S | 01020110079288000 | 22.09.2023 | CD - Rom | 79288.CD |