MARC details
| 000 -LEADER |
|---|
| fixed length control field |
02718cam a2200313 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER |
|---|
| control field |
EG-GiCUC |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
|---|
| fixed length control field |
190928s2019 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE |
|---|
| Original cataloging agency |
EG-GiCUC |
| Language of cataloging |
eng |
| Transcribing agency |
EG-GiCUC |
| 041 0# - LANGUAGE CODE |
|---|
| Language code of text/sound track or separate title |
eng |
| 049 ## - LOCAL HOLDINGS (OCLC) |
|---|
| Holding library |
Deposite |
| 097 ## - Thesis Degree |
|---|
| Thesis Level |
M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
|---|
| Classification number |
Cai01.16.03.M.Sc.2019.Ka.E |
| 100 0# - MAIN ENTRY--PERSONAL NAME |
|---|
| Personal name |
Karim Sayed Metwaly Muhammed |
| 245 14 - TITLE STATEMENT |
|---|
| Title |
The effect of non-target toxicity of deltamethrin in rats in Egypt and South Africa / |
| Statement of responsibility, etc. |
Karim Sayed Metwaly Muhammed ; Supervised Hassan M. Sobhy , Zeinab Yousef Ali |
| 246 15 - VARYING FORM OF TITLE |
|---|
| Title proper/short title |
تأثير السمية غير المستهدفة لمبيد الدلتاميثرين على الجرذان في مصر وجنوب أفريقيا |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
|---|
| Place of publication, distribution, etc. |
Cairo : |
| Name of publisher, distributor, etc. |
Karim Sayed Metwaly Muhammed , |
| Date of publication, distribution, etc. |
2019 |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Extent |
206 P. : |
| Other physical details |
charts , facsimiles ; |
| Dimensions |
25cm |
| 502 ## - DISSERTATION NOTE |
|---|
| Dissertation note |
Thesis (M.Sc.) - Cairo University - Faculty of African Postgraduate Studies - Department of Natural Resources |
| 520 ## - SUMMARY, ETC. |
|---|
| Summary, etc. |
The current thesis focuses on the study of non-target toxicity of Deltamethrin (DLM) in rats, from biochemical and genotoxicity aspects. Also, the other aim of study was to find a mixture of antioxidants (A) to reduce the damage caused by DLM. Initially, LD50 of DLM was determined, which was 135 mg/kg, and the two doses (6.75 mg and 13.5 m /kg b.wt) were used for the treated groups.The results of this study showed significant negative effects on the biochemical and genetic levels, where the blood sugar and (TC) rates increased significantly, where (BChE) and (TAC) where significantly reduced. The liver function was significantly affected by the high rates of (AST), (ALT), (ALP), and (T.B), and reduced the ratio of (T.P).The obtained results of neurotoxicity showed a significant increase in (AChE), (MDA) and (NO), while the activity of Na+/K+ ATPase, (GST) and (GSH) where reduced significantly.Also at the genetic level, DNA is significantly affected by the formation of chromosomal aberrations and micronuclei in the bone marrow, in addition to DNA fragmentation and comets in liver cells. In addition, we used (TNFÜ) and (IL-6) as a biomarker of cellular immune function. Our result shown statistically significant raises in the activity of both biomarkers. In the other hand, Antioxidant mixture showed a significant positive effect in reducing the damage caused by DLM, where the biochemical rates returned close to normal and reduced the damage on the DNA |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE |
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| Additional physical form available note |
Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
Deltamethrin |
| 653 #4 - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
LD50 |
| 653 #4 - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
Non-target toxicity |
| 700 0# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Hassan M. Sobhy , |
| Relator term |
|
| 700 0# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Zeinab Yousef Ali , |
| Relator term |
|
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) |
|---|
| Cataloger |
Nazla |
| Reviser |
Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) |
|---|
| Cataloger |
Shimaa |
| Reviser |
Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| Source of classification or shelving scheme |
Dewey Decimal Classification |
| Koha item type |
Thesis |
