Potential activity of some natural products alone or combined with antibiotic for prevention of gram negative bacterial biofilm / (Record no. 75137)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 03190cam a2200337 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223032435.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 191112s2019 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.08.06.M.Sc.2019.Ra.P |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Rahma Hassanein Ahmed Hassanein |
| 245 10 - TITLE STATEMENT | |
| Title | Potential activity of some natural products alone or combined with antibiotic for prevention of gram negative bacterial biofilm / |
| Statement of responsibility, etc. | Rahma Hassanein Ahmed Hassanein ; Supervised Mohammed Abdelhaleem Ramadan , Wael Mohamed Abu Elwafa |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | الفاعلية المحتملة لبعض المواد الطبيعية بمفردها او مخلوطه بالمضاد الحيوى لمنع بيوفيلم البكتريا سالبة الجرام |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Rahma Hassanein Ahmed Hassanein , |
| Date of publication, distribution, etc. | 2019 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 153 P. : |
| Other physical details | charts , facsimiles ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Microbiology and Immunology |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Microbial biofilms depression represents a major challenge to healthcare because their resistance to conventional antibiotics is dramatically in rise. Therefore, new therapeutic agents for biofilms treatment are urgently needed. This study aims to inhibit and eradicate Pseudomonas aeuroginosa biofilms by 7 plants extracts alone and combined with antibiotic. The results showed that 85% of total PS. aeruginosa isolates were biofilm producers and 25% of these isolates were classified as strong biofilm producers. The highest biofilm capacity and antibiotics resistance was observed with PS-1, which further identified as an isolate of PS. aeruginosa PAO1 by 16S rRNA gene sequencing. Effect of sub-minimum inhibitory concentration levels of these extracts in biofilm formation was investigated. The results showed that, pomegranate and rosemary extracts at 1/2 x MIC levels (3.13 and 6.25 mg/ml, respectively) exhibited the highest biofilm inhibitions (91.93 and 90.83%, respectively) in the present study. Both extracts inhibited biofilm formation by reducing of swimming, swarming and twitching motilities. Biofilm eradication of pomegranate and rosemary extracts alone, mixed, and combined with 5 different antibiotics against 48h-old biofilms was investigated. The results showed that pomegranate/rosemary/ceftazidime combination at MIC level (1.56/ 3.22/ 0.002 mg/ml, respectively) was the most effective combination in biofilm eradication (97.6%). The efficiency of this combination in destroying of biofilm structure and eliminating of bacterial cells had been proven by scanning electron microscope study. Therefore, present study suggests new promising combinations that could be used in PS. aeruginosa biofilm inhibition and eradication |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Biofilm |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Pomegranate |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Pseudomonas |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mohammed Abdelhaleem Ramadan , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Wael Mohamed Abu Elwafa , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Asmaa |
| Reviser | Cataloger |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.08.06.M.Sc.2019.Ra.P | 01010110079785000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.08.06.M.Sc.2019.Ra.P | 01020110079785000 | 22.09.2023 | CD - Rom | 79785.CD |