Urinary osteoprotegerin as a marker of disease activity in juvenile systemic lupus erythematosus / (Record no. 75280)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02753cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223032441.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 191118s2019 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.11.28.M.Sc.2019.Ra.U |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Rana Mohamed Ramadan Hendawy |
| 245 10 - TITLE STATEMENT | |
| Title | Urinary osteoprotegerin as a marker of disease activity in juvenile systemic lupus erythematosus / |
| Statement of responsibility, etc. | Rana Mohamed Ramadan Hendawy ; Supervised Emad Emil Ghobrial , Yomna Mohamed Farag , Mai Hamed Mohamed Kamel |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | إستخدام الأوستيوبروتيجرين فى البول كدلالة لنشاط مرض الذئبة الحمراء فى الأطفال |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Rana Mohamed Ramadan Hendawy , |
| Date of publication, distribution, etc. | 2019 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 137 P. : |
| Other physical details | charts , facsimiles ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pediatrics |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Objectives: Juvenile Systemic lupus erythematosus is an autoimmune disease with multisystem affection and diverse clinical manifestations. Lupus Nephritis is one of the commonest and most serious clinical manifestations of systemic lupus Effective treatment of lupus nephritis requires correct diagnosis, timely intervention and early treatment of any disease relapse Osteoprotegerin (OPG) is produced by the heart, lungs, kidney, and bone.We investigated urinary OPG as potential biomarker for lupus nephritis. Methods: this is a cross sectional study conducted on 60 JSLE patients (27 have active nephritis, 8 have active non renal disease, 10 have inactive nephritis and 15 inactive SLE). Urine samples were collected for OPG measurement by ELISA (pg/ml). Urine samples from 30 healthy individuals served as controls.Results: uOPG was higher in cases than controls (p value<0.001), correlation analysis showed that uOPG levels were significantly correlated with tSELDAI score (r = 0.772, P >0.001), rSLEDAI score (r = 0.828, P < 0.001), Renal Activity Score(r = 0.814, P < 0.001), C3 titre (r = -.590, P < 0.001), C4 titre (r = -.603, P < 0.001) albumin/ creatinine ratio ( P< 0.001) and renal biopsy (P=0.002). Conclusion: uOPG is derived from kidneys and helps to differentiate active SLE patients with LN. It shows modest correlation with disease activity |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Biomarkers |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | JSLE |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Lupus Nephritis |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Emad Emil Ghobrial , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mai Hamed Mohamed Kamel , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Yomna Mohamed Farag , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Shimaa |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.11.28.M.Sc.2019.Ra.U | 01010110080034000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.11.28.M.Sc.2019.Ra.U | 01020110080034000 | 22.09.2023 | CD - Rom | 80034.CD |