The association between WNT1-inducible signaling pathway protein 1 (WISP1) polymorphism and hepatocellular carcinoma in Egyptian patients / (Record no. 75300)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02970cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223032442.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 191119s2019 ua d f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.11.07.M.Sc.2019.Ma.A |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Maha Ahmed Abdelbaky Abdallah |
| 245 14 - TITLE STATEMENT | |
| Title | The association between WNT1-inducible signaling pathway protein 1 (WISP1) polymorphism and hepatocellular carcinoma in Egyptian patients / |
| Statement of responsibility, etc. | Maha Ahmed Abdelbaky Abdallah ; Supervised Mohamed Shehata Abdalla , Hesham Ibrahim Elmakhzangy , Dalia Ahmed Hamed |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | و سرطان الخلايا الكبدية فى المرضى المصريين WISP1 العلاقة بين تعدد أشكال |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Maha Ahmed Abdelbaky Abdallah , |
| Date of publication, distribution, etc. | 2019 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 115 P. : |
| Other physical details | charts ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Clinical and Chemical Pathology |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Background: Hepatocellular carcinoma is the fifth most common form of cancer worldwide and the second most common cause of cancer-related deaths. There are multiple etiologic factors affecting HCC. Chronic hepatitis B and C with associated liver cirrhosis represent major risk factors for HCC development, being implicated in more than 70% of HCC cases worldwide. Many studies have suggested the associations between HCC cancer risk and SNPs in selected genes. Aberrant WISP1 expression may be associated with carcinogenesis. Aim of work: The current study aimed at detecting rs2977530 and rs62514004 polymorphisms of WISP1 gene and susceptibility to HCC in Egyptians. Subjects and Methods: The current case-control study was conducted on 90 subjects classified into two groups: HCC group included 60 patients attending the HCC clinic at Kasr al Ainy Hospitals, compared to a control group including 30 apparently healthy subjects. Genotyping was performed by using Real time-PCR (TaqMan probes). Results: The study showed that no statistically significant association between the WISP1 (rs2977530 and rs62514004) SNPs and the susceptibility to HCC. The laboratory findings in this study revealed statistically significant association between rs62514004 genotype frequencies and two of the laboratory findings: INR and prothrombin time (P value 0.019 and 0.007 with OR 3.953 and 5.844, respectively). While there was no statistically significant association between rs2977530 and HCC risk factors and clinicolaboratory findings |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Hepatocellular carcinoma |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Polymorphism |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | WISP1 |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Dalia Ahmed Hamed , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Hesham Ibrahim Elmakhzangy , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mohamed Shehata Abdalla , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Asmaa |
| Reviser | Cataloger |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.11.07.M.Sc.2019.Ma.A | 01010110080148000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.11.07.M.Sc.2019.Ma.A | 01020110080148000 | 22.09.2023 | CD - Rom | 80148.CD |