Validated modern analytical methods for the determination of some pharmaceutical mixtures / (Record no. 75420)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02771cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223032446.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 191123s2019 ua d f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | Ph.D |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.08.05.Ph.D.2019.Ma.V |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Marwa Ahmed Moffid Allam |
| 245 10 - TITLE STATEMENT | |
| Title | Validated modern analytical methods for the determination of some pharmaceutical mixtures / |
| Statement of responsibility, etc. | Marwa Ahmed Moffid Allam ; Supervised Asmaa Ahmed Elzaher Mohamed , Ehab Farouk Elkady , Hanaa Abdelmonem Hashem |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | طرق تحليلية حديثة متحقق من فاعليتها لتقدير بعض المخاليط الصيدلية |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Marwa Ahmed Moffid Allam , |
| Date of publication, distribution, etc. | 2019 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 191 P. : |
| Other physical details | charts ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (Ph.D.) - Cairo University - Faculty of Pharmacy - Department of Pharmaceutical Chemistry |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | The aim of this work is to develop simple, accurate and precise methods for the determination of some pharmaceutical mixtures in vitro and in human plasma. The drugs were analyzed in their bulk powder and in their pharmaceutical dosage forms either in combinations or in presence combined drugs were determined in plasma. Drugs investigated include Dapagliflozin (SGLT2 inhibitor),Saxagliptin (DPP-4 inhibitor), Metformin (biguanide), Enalapril (ACE-inhibitor), Perindopril (ACEinhibitor), Ramipril (ACE- inhibitor) Atorvastatin calcium and Rosuvastatin calcium (HMG-CoA reductase inhibitor), Ezetimibe (lipid lowering drug), Clopidogrel (adenosine di-phosphate inhibitor) and Telmisartan (angiotensin II blocker) Two LC-MS/MS bioanalytical methods were proposed for the determination of two pharmaceutical mixtures. First mixture is antidiabetic mixture used in treatment of type II diabetes mellitus consisting of dapagliflozin, saxagliptin and metformin. Second mixture consists of three ACE- inhibitors namely, enalapril, perindopril and ramipril. HPLC is a powerful analytical tool for the separation and analysis of pharmaceutical products. It is incorporated in the plan of the work for the estimation of atorvastatin and rosuvastatin in six binary mixtures with other drugs such as ezetimibe, clopidogrel and telmisartan with optimization and application of Box-Behnken experimental design |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Analytical Methods |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Cardiovascular diseases |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Diabetes |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Asmaa Ahmed Elzaher Mohamed , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ehab Farouk Elkady , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Hanaa Abdelmonem Hashem , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Shimaa |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.08.05.Ph.D.2019.Ma.V | 01010110080095000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.08.05.Ph.D.2019.Ma.V | 01020110080095000 | 22.09.2023 | CD - Rom | 80095.CD |