Possible association between microRNA-199a-5p and autophagy related genes in behcet disease / (Record no. 75447)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02629cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223032447.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 191125s2019 ua d f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.11.03.M.Sc.2019.Do.P |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Doaa Saeed Mohamed Zenhom |
| 245 10 - TITLE STATEMENT | |
| Title | Possible association between microRNA-199a-5p and autophagy related genes in behcet disease / |
| Statement of responsibility, etc. | Doaa Saeed Mohamed Zenhom ; Supervised Rania Elsayed Hussein , Radwa Mohammed Gaber Ahmed , Mervat Mahmoud Eissa |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | العلاقة المحتملة بين الحمض النووى الريبوزى المتناهى الصغر ١٩٩-٥ و جينات الالتهام الذاتى فى مرض بهجت |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Doaa Saeed Mohamed Zenhom , |
| Date of publication, distribution, etc. | 2019 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 121 P. : |
| Other physical details | charts ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Medical Biochemistry |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Background: Behcet disease (BD) is a relapsing inflammatory autoimmune disease. MicroRNAs are small RNA fragments that can regulate the gene expression. Autophagy is a protective and life-sustaining process in which cytoplasmic components are targeted to lysosomes for degradation. The aim of this work: To study the association between microRNA199a-5p and ATG5 and Behcet disease activity and severity. Methods: Relative expression of miRNA-199a-5p and ATG5 were measured by Real-Time PCR in blood samples obtained from 47 patients with BD and 50 matched healthy controls. Results: There was a significant higher ESR level in BD patients than controls which highly signifies its autoinflammatory predisposition. Also, there was a significant difference between patients and controls regarding the relative expression of microRNA 199a-5p (p<0.001) with lower expression in patients with BD than in healthy controls and it was significantly lower in patients with thrombophlebitis manifestation. ATG5 relative expression was significantly lower in patients with BD than in healthy controls and ATG5 was significantly higher in behcet patients with arterial thrombosis than other behcet patients |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Autophagy |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Behcet disease (BD) |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | MicroRNA (miRNA) |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mervat Mahmoud Eissa, |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Radwa Mohammed Gaber Ahmed , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Rania Elsayed Hussein , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Shimaa |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.11.03.M.Sc.2019.Do.P | 01010110080099000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.11.03.M.Sc.2019.Do.P | 01020110080099000 | 22.09.2023 | CD - Rom | 80099.CD |