Association between long noncoding RNA taurine up regulated gene 1(TUG1) and microRNA-377 in vitiligo / (Record no. 75460)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02539cam a2200325 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 191125s2019 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.11.03.M.Sc.2019.No.A |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Noura Ragab Abdelazem Abdelrahman |
| 245 10 - TITLE STATEMENT | |
| Title | Association between long noncoding RNA taurine up regulated gene 1(TUG1) and microRNA-377 in vitiligo / |
| Statement of responsibility, etc. | Noura Ragab Abdelazem Abdelrahman ; Supervised Laila Ahmed Rashed , Maha Mohamed Salah Eldin , Maha Fathy Elmasry |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | والحامض النووى الريبوزى المتناهى الصغر 377 فى مرض البهاقTUG1العلاقه بين الحامض النووى الريبوزى الطويل الغير مشفر |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Noura Ragab Abdelazem Abdelrahman , |
| Date of publication, distribution, etc. | 2019 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 121 P. : |
| Other physical details | charts , facsimiles ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Medical Biochemistry |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Background: Vitiligo is the commonest hypopigmented skin disorder. Taurine upregulated gene1(TUG1), one of Long noncoding RNAs (LncRNA) that plays a role in melanogenesis. microRNA-377 (miRNA-377) is a conserved non-coding RNA that regulates angiogenesis and promotes oxidative stress. Peroxisome proliferator-activated receptors (PPARs) are members of the nuclear hormone receptor superfamily. PPARÞ activators stimulate melanogenesis. Interleukin-17(IL17) has been implicated in the pathogenesis of several immunological diseases. Aim: This work aimed to detect the expression levels of TUG1, miRNA-377, PPARÞ and IL-17 among vitiligo subjects and to investigate their possible role in the pathogenesis of vitiligo. Methods: This study was conducted on 30 healthy control and 30 vitiligo patients. TUG1 and miRNA-377 were detected in serum by real- time-PCR, Also PPARÞ and IL-17 were assessed in tissue by Real-time PCR. Results: TUG1and PPARÞ level was significantly down regulated in vitiligo group compared to control group, on the other hand miRNA-377 and IL-17 was significantly up regulated in vitiligo group compared to control group |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | miRNA377 |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | TUG1 |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Vitiligo |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Laila Ahmed Rashed , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Maha Fathy Elmasry , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Maha Mohamed Salah Eldin , |
| Relator term | |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Shimaa |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.11.03.M.Sc.2019.No.A | 01010110080110000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.11.03.M.Sc.2019.No.A | 01020110080110000 | 22.09.2023 | CD - Rom | 80110.CD |