Study of genetic variants in chromosome 5p15.33 region in non-smoker lung cancer patients / (Record no. 75462)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 03003cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223032447.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 191125s2019 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.11.07.M.Sc.2019.Me.S |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Menna Ahmad Elhoussainy Ali |
| 245 10 - TITLE STATEMENT | |
| Title | Study of genetic variants in chromosome 5p15.33 region in non-smoker lung cancer patients / |
| Statement of responsibility, etc. | Menna Ahmad Elhoussainy Ali ; Supervised Iman Mandour , Rania Essam , Sabah Ahmad Hussein |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | دراسة المتغيرات الجينية للكروموسوم 5p15.33فى مرضى سرطان الرئة الغير مدخنين |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Menna Ahmad Elhoussainy Ali , |
| Date of publication, distribution, etc. | 2019 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 136 P. : |
| Other physical details | charts , facsimiles ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Clinical and Chemical Pathology |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Genetic polymorphisms in the telomerase reverse transcriptase (TERT) and cleft lip and palate transmembrane 1-like (CLPTM1L) genes may play important roles in the development of lung cancer in never smokers.The aim of the present study was to evaluate associations between the risk of lung cancer in never smokers and single nucleotide polymorphisms in these genes by Real-Time Taqman assay, in forty lung cancer patients and forty apparently healthy age-matched controls selected from chest department in kasr al Ainy hospital. In the present study, On combining the occurrence of adenocarcinoma and other histopathological subtypes in females versus males it was found that adenocarcinoma was significantly higher in females as compared to other histopathological subtypes while males tend to have other histopathological subtypes and also the prevalence of females having adenocarcinoma is more common than males having adenocarcinoma, the heterozygous form of the CLPT1L occurs more frequently in ages above 46 years old of high clinical significance (with P value 0.019) and near clinical significance association between TERT (rs 2730100) (c. 1574-3777C>A) and CLPT1L (rs 451360) (c. 1532 + 1051C>A) on combing heterozygote form 2CA with CA3 of both genes with lung cancer in never smokers with p value 0.06, but there were no other significant association between other forms,There was no significant association between (rs 2730100) (c. 1574-3777C>A) TERT and incidence of lung cancer in never smokers and There was no significant association between (rs 451360) (c. 1532 + 1051G>T) CLPT1L and incidence of lung cancer in never smokers |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | 5p15.33 |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Genetic variation |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Lung cancer |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Iman Mandour , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Rania Essam , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Sabah Ahmad Hussein , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Shimaa |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.11.07.M.Sc.2019.Me.S | 01010110080112000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.11.07.M.Sc.2019.Me.S | 01020110080112000 | 22.09.2023 | CD - Rom | 80112.CD |