MARC details
| 000 -LEADER |
|---|
| fixed length control field |
02570cam a2200325 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER |
|---|
| control field |
EG-GiCUC |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
191201s2019 ua d f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE |
|---|
| Original cataloging agency |
EG-GiCUC |
| Language of cataloging |
eng |
| Transcribing agency |
EG-GiCUC |
| 041 0# - LANGUAGE CODE |
|---|
| Language code of text/sound track or separate title |
eng |
| 049 ## - LOCAL HOLDINGS (OCLC) |
|---|
| Holding library |
Deposite |
| 097 ## - Thesis Degree |
|---|
| Thesis Level |
Ph.D |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
|---|
| Classification number |
Cai01.11.07.Ph.D.2019.Ha.A |
| 100 0# - MAIN ENTRY--PERSONAL NAME |
|---|
| Personal name |
Hala Ashraf Hosni Abdelaziz |
| 245 10 - TITLE STATEMENT |
|---|
| Title |
Association between superoxide dismutase 2 p.(Ala16Val) and superoxide dismutase 3 p.(Arg213Gly) polymorphisms and risk of neuropathy in Type 1 diabetic patients / |
| Statement of responsibility, etc. |
Hala Ashraf Hosni Abdelaziz ; Supervised Heba Allah M. E. Sharaf Eldeen , Mona Mamdouh A. Hassan , Mai Hamed Mohamed Kamel |
| 246 15 - VARYING FORM OF TITLE |
|---|
| Title proper/short title |
و خطر الاعتلال العصبى فى مرضى السكرى من النوع الأول p.(Arg213Gly) 3و سوبرأوكسيد ديسميوتاز p.(Ala16Val) العلاقة بين تعدد الشكل الجينى لسوبرأوكسيد ديسميوتاز 2 |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
|---|
| Place of publication, distribution, etc. |
Cairo : |
| Name of publisher, distributor, etc. |
Hala Ashraf Hosni Abdelaziz , |
| Date of publication, distribution, etc. |
2019 |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Extent |
111 P. : |
| Other physical details |
charts ; |
| Dimensions |
25cm |
| 502 ## - DISSERTATION NOTE |
|---|
| Dissertation note |
Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Clinical and Chemical Pathology |
| 520 ## - SUMMARY, ETC. |
|---|
| Summary, etc. |
Diabetic neuropathy (DN) is one of the debilitating microvascular complications of diabetes that is present in approximately 50% of patients. Marked increase in oxygen free radicals (OFR) results in oxidative stress that leads to development of DN. Antioxidant enzymes play a major role in protection against rapid onset and progression of DN, by reducing the excess OFR and peroxides. Mutations and variants in genes encoding such enzymes may therefore result in early onset and rapid progression of this complication. Aim: Investigating the association between Superoxide Dismutase 2 p.(Ala16Val) and superoxide dismutase 3 p. (Arg213Gly) gene variants and risk of neuropathy in Type 1 diabetic patients. Methods: Eighty type 1 diabetic patients were divided into two groups, forty patients have clinical DN (Group 1), and forty patients without neuropathy (Group 2). They were all tested for SOD2:p.(Ala16Val) and SOD3:p.(Arg213Gly) gene variants by Taqman Real Time PCR, and HbA1c was done to all patients |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE |
|---|
| Additional physical form available note |
Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
Antioxidants-type 1 diabetes |
| 653 #4 - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
Neuropathy |
| 653 #4 - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
SOD2 gene |
| 700 0# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Heba Allah Mohamed Ebrahim Sharaf Eldeen , |
| Relator term |
|
| 700 0# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Mai Hamed Mohamed Kamel , |
| Relator term |
|
| 700 0# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Mona Mamdouh Abdelghafour Hassan , |
| Relator term |
|
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) |
|---|
| Cataloger |
Nazla |
| Reviser |
Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) |
|---|
| Cataloger |
Samia |
| Reviser |
Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| Source of classification or shelving scheme |
Dewey Decimal Classification |
| Koha item type |
Thesis |
