MARC details
| 000 -LEADER |
|---|
| fixed length control field |
02070cam a2200313 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER |
|---|
| control field |
EG-GiCUC |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
|---|
| fixed length control field |
191201s2019 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE |
|---|
| Original cataloging agency |
EG-GiCUC |
| Language of cataloging |
eng |
| Transcribing agency |
EG-GiCUC |
| 041 0# - LANGUAGE CODE |
|---|
| Language code of text/sound track or separate title |
eng |
| 049 ## - LOCAL HOLDINGS (OCLC) |
|---|
| Holding library |
Deposite |
| 097 ## - Thesis Degree |
|---|
| Thesis Level |
Ph.D |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
|---|
| Classification number |
Cai01.12.04.Ph.D.2019.Sh.M |
| 100 0# - MAIN ENTRY--PERSONAL NAME |
|---|
| Personal name |
Shehab Elbeltagi Mahros Ahmed |
| 245 10 - TITLE STATEMENT |
|---|
| Title |
Multimodal approach of cancer treatment using nanoparticle / |
| Statement of responsibility, etc. |
Shehab Elbeltagi Mahros Ahmed ; Supervised Maha Anwar Ali , Samaa Imam Mahmoud Eldek |
| 246 15 - VARYING FORM OF TITLE |
|---|
| Title proper/short title |
منهجية متعددة لعلاج السرطان باستخدام جسيمات نانومترية |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
|---|
| Place of publication, distribution, etc. |
Cairo : |
| Name of publisher, distributor, etc. |
Shehab Elbeltagi Mahros Ahmed , |
| Date of publication, distribution, etc. |
2019 |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Extent |
108 P. : |
| Other physical details |
charts , facsimiles ; |
| Dimensions |
25cm |
| 502 ## - DISSERTATION NOTE |
|---|
| Dissertation note |
Thesis (Ph.D.) - Cairo University - Faculty of Science - Department of Biophysics |
| 520 ## - SUMMARY, ETC. |
|---|
| Summary, etc. |
Thepreparation of superparamagnetic iron oxide nanoparticles SPIONsNPs byCoprecipitation and Sonochemical methods and coated with polyethylene glycol PEG Fe3O4@PEG and Fe3O4@PEG conjugated Docetaxel. The present study investigatesalternative magnetic field AMF [Zero Voltage Switch ZVS] connected withthe frequency counter and special program. The study aimedto develop the effects of hyperthermia HT and hyperchemothermia HCT on HepG2 cell lines by using ZVS based on SPIONs properties were evaluated. The possible biological effects created by NPs in HepG2 cells such as internalization in the cytoplasm, drug release, cytotoxicity, DNA damage, genotoxic, necrosis, apoptosis,the inhibitory activity of endothelialgrowth factor receptor EGFR,and cell cycle arrest were evaluated. It is concluded that multi-modal approach of HT and HCT treatments induced different cell death program early and late apoptosis due to NPs engulfed byendosomes |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE |
|---|
| Additional physical form available note |
Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
PEG |
| 653 #4 - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
SAR |
| 653 #4 - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
SPIONs |
| 700 0# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Maha Anwar Ali , |
| Relator term |
|
| 700 0# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Samaa Imam Mahmoud Eldek , |
| Relator term |
|
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) |
|---|
| Cataloger |
Nazla |
| Reviser |
Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) |
|---|
| Cataloger |
Samia |
| Reviser |
Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| Source of classification or shelving scheme |
Dewey Decimal Classification |
| Koha item type |
Thesis |
