Study of possible drug interactions between pravastatin and zofenopril in experimentally induced myocardial infarction in irradiated rats / (Record no. 75724)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02875cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223032455.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 191209s2019 ua d f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.08.09.M.Sc.2019.Ne.S |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Nehal Mohamed Mohamed Mansour |
| 245 10 - TITLE STATEMENT | |
| Title | Study of possible drug interactions between pravastatin and zofenopril in experimentally induced myocardial infarction in irradiated rats / |
| Statement of responsibility, etc. | Nehal Mohamed Mohamed Mansour ; Supervised Mostafa E. Elsayed , Hala Fahmy Zaki , Seham Hassan Mohamed Hassan |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | دراسة التداخلات الدوائية المحتملة بين برافاستاتين و زوفينوبريل في الجرذان المشععةالمحدث لها إحتشاء بعضلة القلب |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Nehal Mohamed Mohamed Mansour , |
| Date of publication, distribution, etc. | 2019 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 123 P. : |
| Other physical details | charts , facsimiles ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Pharmacology and Toxicology |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | The present work aimed to investigate the potential protective effect of zofenopril (ZF; 15 mg/kg/day; p.o.) and/or pravastatin (PR; 40 mg/kg/day; p.o.), respectively against isoprenaline (ISO)-induced acute myocardial infarction (AMI) in irradiated (IRR) rats. Rats were allocated into seven groups (n=10), (GP-I) normal-control group received distilled water, (GP-II) exposed to single dose (5Gy) gamma-irradiation, (GP-III) ISO group received ISO at doses of 85 and 170 mg/kg, subcutaneously, for 2 days with a 24-hr interval, (GP-IV) ISO-IRR group exposed to 5Gy IRR then received ISO at doses of 85 and 170 mg/kg, subcutaneously, for 2 days with a 24-hr interval, (GP-V) & (GP-VI) received ZF or PR, respectively, for 5days prior IRR and ISO, (GP-VII) received combined ZF and PR pretreatment for 5days prior IRR and ISO. Parameters for evaluation the protective effect of the tested drugs included serum levels of tumor necrosis factor-alpha (TNF-Ü), high-sensitivity C-reactive protein (Hs-CRP) and activities of creatine kinase (CK-MB), lactate dehydrogenase (LDH) andaspartate transaminase (AST) as well as lipid profile, in addition to, cardiac tissue activities of superoxide dismutase (SOD) and catalase and levels of malondialdehyde (MDA) and glutathione (GSH). Histopathological examination of cardiac tissue was also carried out |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Acute myocardial infarction |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Pravastatin |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Zofenopril |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Hala Fahmy Zaki , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mostafa E. Elsayed , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Seham Hassan Mohamed Hassan , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Shimaa |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.08.09.M.Sc.2019.Ne.S | 01010110080262000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.08.09.M.Sc.2019.Ne.S | 01020110080262000 | 22.09.2023 | CD - Rom | 80262.CD |