Biochemical studies of hippocampal gene expression of brain toll like receptor in diabetic&derived neurotrophic factor rats exposed to chronic restraint stress : (Record no. 75739)
[ view plain ]
| 000 -LEADER | |
|---|---|
| fixed length control field | 02465cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223032456.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 191209s2019 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | Ph.D |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.12.02.Ph.D.2019.Do.B |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Doaa Mohamed Hassan |
| 245 10 - TITLE STATEMENT | |
| Title | Biochemical studies of hippocampal gene expression of brain toll like receptor in diabetic&derived neurotrophic factor rats exposed to chronic restraint stress : |
| Remainder of title | Effect of antidepressant drugs / |
| Statement of responsibility, etc. | Doaa Mohamed Hassan ; Supervised Ismail Abdelshafy Abdelhamid , Ahmed Ibrahim Amin , Samar Kamal Kassim |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | دراسات كيميائية حيوية على التعبيرالجينى فى قرن امون لعامل التغذية العصبية المخية و مستقبل التول ليك فى الفئران المصابة بمرض السكر والمعرضة للضغط العصبى المزمن : |
| Remainder of title | تأثير مضادات الأكتئاب |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Doaa Mohamed Hassan , |
| Date of publication, distribution, etc. | 2019 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 156 P. : |
| Other physical details | charts , facsimiles ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (Ph.D.) - Cairo University - Faculty of Science - Department of Biochemistry |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | This work investigates the alteration in gene expression of BDNF and TLR4 in the hippocampus of diabetic rats and non-diabetic maleWistar rats exposed to chronic restraint stress.Study included eight groups were used. fourgroups include: 1-Naïve rats, 2-non-diabetic CRS vehicle treated, 3-non-diabetic CRS fluoxetine treated&4- non-diabetic CRS imipramine treated; the same four groups with diabetic rats. Laboratory investigation were determined by using semi quantitative RT-PCR&ELISA. Diabetic rats & rats expose to CRS show significant decrease in gene expression & protein of BDNF with significant increase in in gene expression & protein of TLR4. It is concluded that BDNF & TLR genes has effective role with inflammatory state &stress and act in contrary manner and the preferable of fluoxetine over imipramine |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | BDNF |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Fluoxetine |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | TLR4 |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ahmed Ibrahim Amin , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ismail Abdelshafy Abdelhamid , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Samar Kamal Kassim , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Shimaa |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.12.02.Ph.D.2019.Do.B | 01010110080268000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.12.02.Ph.D.2019.Do.B | 01020110080268000 | 22.09.2023 | CD - Rom | 80268.CD |