Phytochemical and biological studies of Phyllanthus emblica and Ficus benghalensis on female reproductive function in rats / (Record no. 76178)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 03165cam a2200325 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 191230s2019 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | Ph.D |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.08.07.Ph.D.2019.Sa.P |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Sally Eid Morsy Khaled |
| 245 10 - TITLE STATEMENT | |
| Title | Phytochemical and biological studies of Phyllanthus emblica and Ficus benghalensis on female reproductive function in rats / |
| Statement of responsibility, etc. | Sally Eid Morsy Khaled ; Supervised Fatma Abdelmegeed Hashem , Mohamed Ali Ali Farag , Manal Hassan Shabana |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | دراسات فيتوكيميائية و بيولوجية لنباتى فيلانثس إمبليكا و فيكس بنجالنسس على الوظائف التكاثرية لإناث الفئران |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Sally Eid Morsy Khaled , |
| Date of publication, distribution, etc. | 2019 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 302 P. : |
| Other physical details | charts , facsimiles ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (Ph.D.) - Cairo University - Faculty of Pharmacy - Department of Pharmacognosy |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Phyllanthus emblica L. fruits and Ficus benghalensis aerial roots have long been used in Ayurvedic medicine for their many health benefits. This study attempts to justify biochemically the traditional use of the aforementioned plants in treatment of female reproductive disorders in relation to their secondary metabolite profile. The effect of the total ethanol extract and successive fractions of these plants on the female reproductive system was evaluated by assessing their estrogenic and gonadotropic activities. Results revealed that the non-polar petroleum ether and chloroform fractions of P. emblica exhibited the strongest estrogenic activity besides gonadotropic activity, while n-butanol fraction exhibited a significant follicle stimulating hormone-like [FSH] activity and luteinizing hormone-like [LH] activity. Regarding F. benghalensis, only non-polar petroleum ether and chloroform fraction exhibited moderate estrogenic and FSH-like activity with no LH-like activity. To pinpoint active agents in these fractions, metabolite profiling was attempted via UPLC-MS and GC-MS. UPLC-MS annotated 92 and 84 metabolites in P. emblica fruit and F. benghalensis aerial root, respectively. Secondary metabolites annotated in P. emblica included ellagitannins, gallic acid derivatives, terpenoids, sterols, phthalates and fatty acids.The active non-polar fractions of F.benghalensis revealed similar metabolites profile being composed of isoflavonoids, triterpenes, sterols, fatty acids and cyclic peptides; likely to mediate for its effects. GC-MS analysis of the non-polar bioactive fractions was further employed revealing the enrichment of non-polar fractions of both plants in fatty acids/fatty acyl esters, terpenes and phenolic compounds |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Estrogenic activity |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Ficus benghalensis |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Phyllanthus emblica |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Fatma Abdelmegeed Hashem , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Manal Hassan Shabana , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mohamed Ali Ali Farag , |
| Relator term | |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Shimaa |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.08.07.Ph.D.2019.Sa.P | 01010110080548000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.08.07.Ph.D.2019.Sa.P | 01020110080548000 | 22.09.2023 | CD - Rom | 80548.CD |