Prognostic value of metformin in locally advanced irresectable non small cell lung cancer patients / (Record no. 76260)
[ view plain ]
| 000 -LEADER | |
|---|---|
| fixed length control field | 02585cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223032511.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 200111s2019 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.19.04.M.Sc.2019.Fa.P |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Fatma Sami Eissa |
| 245 10 - TITLE STATEMENT | |
| Title | Prognostic value of metformin in locally advanced irresectable non small cell lung cancer patients / |
| Statement of responsibility, etc. | Fatma Sami Eissa ; Supervised Ahmed Elsaied Elbastawisy , Shereen Mostafa Elshorbagy , Rimon Ramsis Anis |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | النتائج والسمات التنبؤية لعقار الميتفورمين فى مرضي المصابين بسرطان الرئة المتقدم محليا والغير قابل للاستئصال |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Fatma Sami Eissa , |
| Date of publication, distribution, etc. | 2019 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 101 P. : |
| Other physical details | charts , facsimiles ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (M.Sc.) - Cairo University - National Cancer Institute - Department of Oncology (Medical) |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Locally advanced NSCLC is frequently inoperable and treated with combined chemoradiotherapy with poor outcomes due to high resistance to chemotherapy. Metformin, a first line anti diabetic medication, was found to have an anti-tumor effect. The study is a prospective study evaluating the efficacy and toxicity of adding metformin to concomitant chemo-radiotherapy using platinum based chemotherapy (paclitaxel 45mg\m2,carboplatin AUC 2 weekly with thoracic radiation of 60 Gy in 30 fractions over 6 weeks in locally advanced irresectable non small cell lung cancer patients. We enrolled 30 patients of locally advanced irresectable lung cancer patients and divided into two groups . Group A included 15 patients received concomitant chemo-radiotherapy with metformin and group B received concomitant chemo-radiotherapy without metformin and concluded no statistically significant difference were found between the two groups as regard clinical response and over all clinical benefit and was tolerable. Adding metformin to concurrent in locally advanced irresectable NSCLC patients improved the PFS but did not effect the OS at one year follow up |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Chemoradiotherapy |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Metformin |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | NSCLC |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ahmed Elsaied Elbastawisy , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Rimon Ramsis Anis , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Shereen Mostafa Elshorbagy , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Shimaa |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.19.04.M.Sc.2019.Fa.P | 01010110080574000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.19.04.M.Sc.2019.Fa.P | 01020110080574000 | 22.09.2023 | CD - Rom | 80574.CD |