MARC details
000 -LEADER |
fixed length control field |
02826cam a2200325 a 4500 |
003 - CONTROL NUMBER IDENTIFIER |
control field |
EG-GiCUC |
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
fixed length control field |
200111s2019 ua dh f m 000 0 eng d |
040 ## - CATALOGING SOURCE |
Original cataloging agency |
EG-GiCUC |
Language of cataloging |
eng |
Transcribing agency |
EG-GiCUC |
041 0# - LANGUAGE CODE |
Language code of text/sound track or separate title |
eng |
049 ## - LOCAL HOLDINGS (OCLC) |
Holding library |
Deposite |
097 ## - Thesis Degree |
Thesis Level |
M.Sc |
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
Classification number |
Cai01.12.25.M.Sc.2019.Na.S |
100 0# - MAIN ENTRY--PERSONAL NAME |
Personal name |
Nawal Ahmed Sayed Ibrahium Elabasawy |
245 10 - TITLE STATEMENT |
Title |
Study of teratogenic effects after verapamil administration in pregnant albino rats / |
Statement of responsibility, etc. |
Nawal Ahmed Sayed Ibrahium Elabasawy ; Supervised Mohamed Ahmed Badwy , Abdelwahab Elghareeb , Heba Ali Abdelrahman |
246 15 - VARYING FORM OF TITLE |
Title proper/short title |
دراسة التأثيرات المشوهة بعد تناول عقار فيراباميل على الجزران البيضاء الحوامل |
260 ## - PUBLICATION, DISTRIBUTION, ETC. |
Place of publication, distribution, etc. |
Cairo : |
Name of publisher, distributor, etc. |
Nawal Ahmed Sayed Ibrahium Elabasawy , |
Date of publication, distribution, etc. |
2019 |
300 ## - PHYSICAL DESCRIPTION |
Extent |
98 P. : |
Other physical details |
charts , facsimiles ; |
Dimensions |
25cm |
502 ## - DISSERTATION NOTE |
Dissertation note |
Thesis (M.Sc.) - Cairo University - Faculty of Science - Department of Biotechnology |
520 ## - SUMMARY, ETC. |
Summary, etc. |
This study was conducted in an attempt to prove the teratogenic potential of Verapamil on pregnant rat's offspring. Female rats were administrated with Verapamil (0.1 mg/Kg) by gastric tube from 5th to 19th day of pregnancy. At 20th day the animals were sacrificed and dissected in order to remove the uterus then open it to get the fetuses and record the mortality rate, growth parameters, skeletal malformations, histological study of placenta, fetal liver, mother liver.The results could be summarized in the following points: The pregnant rats treated orally with therapeutically dose of Verapamil during gestation period (5th - 19 th) showed no external signs of toxicity (nasal or vaginal bleeding) and no mortality cases were recorded but there was a non-significant decrease in the mother weight gain of the treated group when compared with the control.There was a significant decrease in the placental weight throughout the treated group (0.395± 0.022a ) when compared with the control (0.515 ± 0.08).The treated pregnant rat's uterus showed asymmetrical distribution of fetuses in the two uteri horns and reduced number of fetuses, uterine horns showing clearly visible embryonic resorbed sites.The treated group showed a reduction in the pre-implantation loss index % and increased in the pre- and post-implantation loss index% There were a significant (P{u2264} 0.05) reduction in fetus weight (1.80 ± 1.48a ) of animals from treated group in comparison with the control one (2.900 ± 0.775) |
530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE |
Additional physical form available note |
Issued also as CD |
653 #4 - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
Pregnant |
653 #4 - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
Teratology |
653 #4 - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
Verapamil |
700 0# - ADDED ENTRY--PERSONAL NAME |
Personal name |
Abdelwahab Elghareeb , |
Relator term |
|
700 0# - ADDED ENTRY--PERSONAL NAME |
Personal name |
Heba Ali Abdelrahman, |
Relator term |
|
700 0# - ADDED ENTRY--PERSONAL NAME |
Personal name |
Mohamed Ahmed Badwy , |
Relator term |
|
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) |
Cataloger |
Nazla |
Reviser |
Revisor |
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) |
Cataloger |
Shimaa |
Reviser |
Cataloger |
942 ## - ADDED ENTRY ELEMENTS (KOHA) |
Source of classification or shelving scheme |
Dewey Decimal Classification |
Koha item type |
Thesis |