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Study of teratogenic effects after verapamil administration in pregnant albino rats / (Record no. 76275)

MARC details
000 -LEADER
fixed length control field 02826cam a2200325 a 4500
003 - CONTROL NUMBER IDENTIFIER
control field EG-GiCUC
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 200111s2019 ua dh f m 000 0 eng d
040 ## - CATALOGING SOURCE
Original cataloging agency EG-GiCUC
Language of cataloging eng
Transcribing agency EG-GiCUC
041 0# - LANGUAGE CODE
Language code of text/sound track or separate title eng
049 ## - LOCAL HOLDINGS (OCLC)
Holding library Deposite
097 ## - Thesis Degree
Thesis Level M.Sc
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC)
Classification number Cai01.12.25.M.Sc.2019.Na.S
100 0# - MAIN ENTRY--PERSONAL NAME
Personal name Nawal Ahmed Sayed Ibrahium Elabasawy
245 10 - TITLE STATEMENT
Title Study of teratogenic effects after verapamil administration in pregnant albino rats /
Statement of responsibility, etc. Nawal Ahmed Sayed Ibrahium Elabasawy ; Supervised Mohamed Ahmed Badwy , Abdelwahab Elghareeb , Heba Ali Abdelrahman
246 15 - VARYING FORM OF TITLE
Title proper/short title دراسة التأثيرات المشوهة بعد تناول عقار فيراباميل على الجزران البيضاء الحوامل
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Place of publication, distribution, etc. Cairo :
Name of publisher, distributor, etc. Nawal Ahmed Sayed Ibrahium Elabasawy ,
Date of publication, distribution, etc. 2019
300 ## - PHYSICAL DESCRIPTION
Extent 98 P. :
Other physical details charts , facsimiles ;
Dimensions 25cm
502 ## - DISSERTATION NOTE
Dissertation note Thesis (M.Sc.) - Cairo University - Faculty of Science - Department of Biotechnology
520 ## - SUMMARY, ETC.
Summary, etc. This study was conducted in an attempt to prove the teratogenic potential of Verapamil on pregnant rat's offspring. Female rats were administrated with Verapamil (0.1 mg/Kg) by gastric tube from 5th to 19th day of pregnancy. At 20th day the animals were sacrificed and dissected in order to remove the uterus then open it to get the fetuses and record the mortality rate, growth parameters, skeletal malformations, histological study of placenta, fetal liver, mother liver.The results could be summarized in the following points: The pregnant rats treated orally with therapeutically dose of Verapamil during gestation period (5th - 19 th) showed no external signs of toxicity (nasal or vaginal bleeding) and no mortality cases were recorded but there was a non-significant decrease in the mother weight gain of the treated group when compared with the control.There was a significant decrease in the placental weight throughout the treated group (0.395± 0.022a ) when compared with the control (0.515 ± 0.08).The treated pregnant rat's uterus showed asymmetrical distribution of fetuses in the two uteri horns and reduced number of fetuses, uterine horns showing clearly visible embryonic resorbed sites.The treated group showed a reduction in the pre-implantation loss index % and increased in the pre- and post-implantation loss index% There were a significant (P{u2264} 0.05) reduction in fetus weight (1.80 ± 1.48a ) of animals from treated group in comparison with the control one (2.900 ± 0.775)
530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE
Additional physical form available note Issued also as CD
653 #4 - INDEX TERM--UNCONTROLLED
Uncontrolled term Pregnant
653 #4 - INDEX TERM--UNCONTROLLED
Uncontrolled term Teratology
653 #4 - INDEX TERM--UNCONTROLLED
Uncontrolled term Verapamil
700 0# - ADDED ENTRY--PERSONAL NAME
Personal name Abdelwahab Elghareeb ,
Relator term
700 0# - ADDED ENTRY--PERSONAL NAME
Personal name Heba Ali Abdelrahman,
Relator term
700 0# - ADDED ENTRY--PERSONAL NAME
Personal name Mohamed Ahmed Badwy ,
Relator term
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN)
Cataloger Nazla
Reviser Revisor
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN)
Cataloger Shimaa
Reviser Cataloger
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme Dewey Decimal Classification
Koha item type Thesis
Holdings
Source of classification or shelving scheme Not for loan Home library Current library Date acquired Full call number Barcode Date last seen Koha item type Copy number
Dewey Decimal Classification   المكتبة المركزبة الجديدة - جامعة القاهرة قاعة الرسائل الجامعية - الدور الاول 11.02.2024 Cai01.12.25.M.Sc.2019.Na.S 01010110080611000 22.09.2023 Thesis  
Dewey Decimal Classification   المكتبة المركزبة الجديدة - جامعة القاهرة مخـــزن الرســائل الجـــامعية - البدروم 11.02.2024 Cai01.12.25.M.Sc.2019.Na.S 01020110080611000 22.09.2023 CD - Rom 80611.CD