Risk factors (pre and post transplant) in relation to the outcome of allogeneic stem cell transplantation in pediatric cancer patients / (Record no. 77021)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 03278cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223032535.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 200706s2020 ua d f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | Ph.D |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.19.05.Ph.D.2020.Ha.R |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Hanaa Rashad Mahmoud |
| 245 10 - TITLE STATEMENT | |
| Title | Risk factors (pre and post transplant) in relation to the outcome of allogeneic stem cell transplantation in pediatric cancer patients / |
| Statement of responsibility, etc. | Hanaa Rashad Mahmoud ; Supervised Alaa Mohamed Elhaddad , Lobna M. Elamin Shalaby , Nayra Hamdy Elshakankiry |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | عوامل الخطورة ( قبل وبعد زرع النخاع) وعلاقتها بنتائج زرع الخلايا الجذعية من متبرع فى سرطان الأطفال |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Hanaa Rashad Mahmoud , |
| Date of publication, distribution, etc. | 2020 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 111 P. : |
| Other physical details | charts , facsimiles ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (Ph.D.) - Cairo University - National Cancer Institute - Department of Pediatric Oncology |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Background/Objectives; A balanced risk-benefit approach to hematopoietic cell transplantation (HCT), with accurate assessment of underlying risk factors related to the outcome is the key for maximized chances of cure with acceptable quality of life in pediatric patients with advanced hematologic malignancies. This study aimed to assess different risk factors that affect the outcome of allogeneic HSCT in pediatric cancer patients and Formulate comorbidity index that predict the transplant related morbidity and mortality. Patients and Methods; A retrospective study included pediatric cancer patients who underwent allogeneic HSCT at the HSCT unit, Cancer Hospital Egypt (CCHE), from January 2011 and January 2019. Impact of different pre and post transplant risk factors on the outcome of these patients was analyzed. Results: A total of 159 patients were included with median age of 8.8 years and male to female ratio 1.4:1. Based on our Disease Risk Stratification19% of the patients were classified as LR group (CML), 51.6% as IR (AML CR1, ALL, MDS) and 28.3% of them were HR group (AML CR2 and JMML). From the whole study patients, (86.8%) received Allograft from matched related donors (MRD), 16 (10.1%) from Haploidentical donors and 5 (3.1%) from Mismatched related donors (MMRD). Bone marrow was used as stem cell source for 92.5 % of the patients While Mobilized Peripheral blood was used in 7.5%. With median duration of follow up of 64 months, the 3-year overall survival of the Whole patients was 64% and non-relapse mortality was 7.5%. Age of the patient, Disease risk and HLA matching were the 3 factors statistically significant in Cox regression with worst survival outcome was associated with younger age < 6 years, HR disease group and haploidentical transplant |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Allogeneic stem cell transplantation |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Pediatrics |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Transplant |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Alaa Mohamed Elhaddad , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Lobna M. Elamin Shalaby , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Nayra Hamdy Elshakankiry , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Shimaa |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.19.05.Ph.D.2020.Ha.R | 01010110080961000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.19.05.Ph.D.2020.Ha.R | 01020110080961000 | 22.09.2023 | CD - Rom | 80961.CD |