Extended letrozole regimen co-treatment with gonadotropin releasing hormone antagonist protocol versus gonadotropin releasing hormone antagonist protocol in poor responders undergoing IVF-ET : (Record no. 77238)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 03301cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223032542.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 200817s2020 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | Ph.D |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.11.15.Ph.D.2020.Ah.E |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Ahmed Shamel Moustafa Hefny |
| 245 10 - TITLE STATEMENT | |
| Title | Extended letrozole regimen co-treatment with gonadotropin releasing hormone antagonist protocol versus gonadotropin releasing hormone antagonist protocol in poor responders undergoing IVF-ET : |
| Remainder of title | A randomized controlled trial / |
| Statement of responsibility, etc. | Ahmed Shamel Moustafa Hefny ; Supervised Mostafa Mohamed Elsadek , Usama Mohamed Fikry Fouda , Mariam Ahmed Dawoud |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | دراسة مقارنة عشوائية محكمة بين الجرعة الممتدة من عقار ليتروزول بالاضافه لبروتوكول مضاد مطلق الجونادوتروبين مقابل بروتوكول مضاد مطلق الجونادوتروبين لعلاج الحالات التى تعاني من ضعف الاستجابة اثناء اجراء الاخصاب فى المختبر |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Ahmed Shamel Moustafa Hefny , |
| Date of publication, distribution, etc. | 2020 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 110 P. : |
| Other physical details | charts , facsimiles ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Gynecology and Obstetrics |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Objective To evaluate the efficacy of extended letrozole co-treatment with GnRHantagonist protocol in ovarian stimulation of poor responder patients undergoing IVF-ET. Methods This prospective, double blinded, two arm randomized controlled trial was conducted at assisted conception unit of Obstetrics and Gynecology department, Cairo university, Egypt, between May 2018 and January 2020. The study included 106 fresh IVF-ET cycles from 106 poor responders according to the Bologna criteria. Patients were randomized in 1: 1 ratio to extended letrozole regimen / GnRH antagonist protocol group and GnRH antagonist protocol group. In extended letrozole regimen / GnRH ant group letrozole was administered starting on cycle day 1 for 8 consecutive days.The dose of letrozole was (5 mg/day during the first 5 days of cycle and 2.5 mg/ day during the subsequent 3 days). In GnRH antagonist group, placebo tablets were administered. In both groups, GnRH antagonist (Cetrorelix acetate) 0.25 mg S.C. once daily was started when the leading follicle was 14 mm in mean diameter. Results Total cycle cancellation rate and cycle cancelation rate due to poor response were comparable between both groups (28.3% Vs. 30.19%, P value = 0.831 and 16.18% Vs 20.59%, P value = 0.605, respectively). The number of follicles {u2265}18 mm, oocytes retrieved, metaphase II oocyte, 2PN embryos, transferred embryos, peak estradiol level and quality of VII transferred embryos were comparable between both groups |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | GnRH antagonist |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Letrozole |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Poor responders |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mariam Ahmed Dawoud , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mostafa Mohamed Elsadek , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Usama Mohamed Fikry Fouda , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Shimaa |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.11.15.Ph.D.2020.Ah.E | 01010110081209000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.11.15.Ph.D.2020.Ah.E | 01020110081209000 | 22.09.2023 | CD - Rom | 81209.CD |