Nucleophosmin mutations in De novo adult acute myeloid leukemia and its prognostic impact / (Record no. 77305)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02445cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223032544.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 200822s2020 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | Ph.D |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.19.03.Ph.D.2020.La.N |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Lamiaa Nabih Helal Elfadali |
| 245 10 - TITLE STATEMENT | |
| Title | Nucleophosmin mutations in De novo adult acute myeloid leukemia and its prognostic impact / |
| Statement of responsibility, etc. | Lamiaa Nabih Helal Elfadali ; Supervised Khaled Mostafa Aboulenein , Naglaa Mostafa Hassan Ahmed , Raafat Mohammad Abdelfattah |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | دراسة تكرار طفرة جين النيوكليوفوزمين فى حالات سرطان الدم الميلودى الحاد الجديدة لدى البالغين |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Lamiaa Nabih Helal Elfadali , |
| Date of publication, distribution, etc. | 2020 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 143 P. : |
| Other physical details | charts , facsimiles ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (Ph.D.) - Cairo University - National Cancer Institute - Department of Clinical Pathology |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Aim:To evaluate the frequency of NPM mutation A in denovo adult AML and to evaluate its relation with clinical and laboratory parameters and with response to treatment. Patients and Methods: 89 patients were included in our study, taking BM samples, RNA extraction and quantitative RT-PCR were done to detect the frequency of NPM1 mutation A. Results:We found NPM1 mutation in 33/89 (37.1) AML patients of which NPM mutation A was found in 6/33 (18.1%) NPM mutated AML patients and was 6/89 (6.7%) of AML patients. 24/33 (72.7%) NPM mutated patients were died before day 28 of treatment. 9/33 (27.3%) NPM mutant patients achieved CR. 5/6 (83.3%) NPM mutation A patients died before D28 of treatment and 1/6 (6.7%) NPM mutation A patient achieve CR with no statistically significance. Conclusions:We found that frequency of NPM gene mutation was 37% of AML patients and NPM gene mutation A was 18% of NPM1 mutation and 6.7 of AML patients |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Activities of daily living (ADL) |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Acute myeloid leukemia |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Nucleophosmin gene mutation |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Khaled Mostafa Aboulenein , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Naglaa Mostafa Hassan Ahmed , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Raafat Mohammad Abdelfattah , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Shimaa |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.19.03.Ph.D.2020.La.N | 01010110081241000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.19.03.Ph.D.2020.La.N | 01020110081241000 | 22.09.2023 | CD - Rom | 81241.CD |