MARC details
000 -LEADER |
fixed length control field |
02989cam a2200325 a 4500 |
003 - CONTROL NUMBER IDENTIFIER |
control field |
EG-GiCUC |
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
fixed length control field |
200823s2019 ua dh f m 000 0 eng d |
040 ## - CATALOGING SOURCE |
Original cataloging agency |
EG-GiCUC |
Language of cataloging |
eng |
Transcribing agency |
EG-GiCUC |
041 0# - LANGUAGE CODE |
Language code of text/sound track or separate title |
eng |
049 ## - LOCAL HOLDINGS (OCLC) |
Holding library |
Deposite |
097 ## - Thesis Degree |
Thesis Level |
M.Sc |
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
Classification number |
Cai01.11.21.M.Sc.2019.No.O |
100 0# - MAIN ENTRY--PERSONAL NAME |
Personal name |
Nouran Alaa Mahmoud Abdelhamid |
245 10 - TITLE STATEMENT |
Title |
Optical coherence tomography and optical coherence tomography angiography in multiple sclerosis patients / |
Statement of responsibility, etc. |
Nouran Alaa Mahmoud Abdelhamid ; Supervised Adel Hassanein Elsayed Gad , Lobna Ahmed Talaat Elghoneimy , Randa Mohamed Abdelmoneim Elmofty |
246 15 - VARYING FORM OF TITLE |
Title proper/short title |
تصوير التماسك البصرى المقطعى و تصوير التماسك البصرى المقطعى على الأوعية الدموية بالشبكية فى مرضى التصلب المتعدد |
260 ## - PUBLICATION, DISTRIBUTION, ETC. |
Place of publication, distribution, etc. |
Cairo : |
Name of publisher, distributor, etc. |
Nouran Alaa Mahmoud Abdelhamid , |
Date of publication, distribution, etc. |
2019 |
300 ## - PHYSICAL DESCRIPTION |
Extent |
166 P. : |
Other physical details |
charts , facsimiles ; |
Dimensions |
25cm |
502 ## - DISSERTATION NOTE |
Dissertation note |
Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Neuropsychiatry |
520 ## - SUMMARY, ETC. |
Summary, etc. |
Background: Optical coherence tomography (OCT) has developed into a sensitive method for the evaluation of optic nerve and retinal pathology in multiple sclerosis (MS). Optical coherence tomography angiography (OCT-A) is a new method to assess the density of the vascular networks. Vascular abnormalities are considered involved in multiple sclerosis (MS) pathology. They could also play an important role in the pathogenesis of MS lesions and disease progression. Objective: The aim of our study was to assess the presence of vascular abnormalities in MS, to evaluate their correlation to disease features and to detect whether vasculopathy could be part of MS pathogenesis.Our study also aimed at providing a possibility that the retinal vasculature may be a biomarker of neurodegeneration and disease progression. Methods: A total of 30 MS patients with and without history of optic neuritis (ON) and 10 healthy subjects were included. All underwent spectral domain (SD)-OCT and OCT angiography. Clinical history, (EDSS), disease duration, visual function testing and investigations were all collected. Results: A statistically significant reduction in all SD-OCT and OCT angiography parameters was noticed both in eyes with and without ON when compared with control eyes. OCT showed nerve thickness reduction and OCT-A showed a vessel density reduction in eyes of MS patients. We found a direct correlation between SD-OCT parameters and between vessel density parameters (p = < 0.001) |
530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE |
Additional physical form available note |
Issued also as CD |
653 #4 - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
Multiple sclerosis |
653 #4 - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
Optical Coherence Tomography (OCT) |
653 #4 - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
Retinal vascular abnormalities |
700 0# - ADDED ENTRY--PERSONAL NAME |
Personal name |
Adel Hassanein Elsayed Gad , |
Relator term |
|
700 0# - ADDED ENTRY--PERSONAL NAME |
Personal name |
Lobna Ahmed Talaat Elghoneimy , |
Relator term |
|
700 0# - ADDED ENTRY--PERSONAL NAME |
Personal name |
Randa Mohamed Abdelmoneim Elmofty , |
Relator term |
|
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) |
Cataloger |
Nazla |
Reviser |
Revisor |
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) |
Cataloger |
Shimaa |
Reviser |
Cataloger |
942 ## - ADDED ENTRY ELEMENTS (KOHA) |
Source of classification or shelving scheme |
Dewey Decimal Classification |
Koha item type |
Thesis |