MARC details
| 000 -LEADER |
|---|
| fixed length control field |
02726cam a2200325 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER |
|---|
| control field |
EG-GiCUC |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
|---|
| fixed length control field |
200829s2020 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE |
|---|
| Original cataloging agency |
EG-GiCUC |
| Language of cataloging |
eng |
| Transcribing agency |
EG-GiCUC |
| 041 0# - LANGUAGE CODE |
|---|
| Language code of text/sound track or separate title |
eng |
| 049 ## - LOCAL HOLDINGS (OCLC) |
|---|
| Holding library |
Deposite |
| 097 ## - Thesis Degree |
|---|
| Thesis Level |
M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
|---|
| Classification number |
Cai01.11.24.M.Sc.2020.Mo.R |
| 100 0# - MAIN ENTRY--PERSONAL NAME |
|---|
| Personal name |
Mohamed Saad Emam Ahmed |
| 245 10 - TITLE STATEMENT |
|---|
| Title |
Role oF OCT-A to detect possible retinal vascular complications of sofosbuvir (sovaldi) in patients with hepatitis C virus infection / |
| Statement of responsibility, etc. |
Mohamed Saad Emam Ahmed ; Supervised Magda Salaheldin Abdelaziz Ahmed , Hany Elmekawey Elmekawey , Yomna Amr Abdelwahab |
| 246 15 - VARYING FORM OF TITLE |
|---|
| Title proper/short title |
دور اىشعة المقطعية الضوئية المتداخلة للأوعية الدموية فى اكتشاف مضاعفات شبكية العين الممكن حدوثها مع عقار السوفوسبوفير (سوفالدى) فى مرضى الالتهاب الكبدى الوبائى - سى |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
|---|
| Place of publication, distribution, etc. |
Cairo : |
| Name of publisher, distributor, etc. |
Mohamed Saad Emam Ahmed , |
| Date of publication, distribution, etc. |
2020 |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Extent |
113 P. : |
| Other physical details |
charts , facsimiles ; |
| Dimensions |
25cm |
| 502 ## - DISSERTATION NOTE |
|---|
| Dissertation note |
Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Ophthalmology |
| 520 ## - SUMMARY, ETC. |
|---|
| Summary, etc. |
Purpose: The purpose of this study is to evaluate the value of optical coherence tomography angiography (OCT-A) for the of detection of any suspected retinal complications associated with use of combined therapy (Sofosbuvir "Sovaldi" and Daclatasvir "Daklinza") in Patients With Hepatitis C Virus Infection Design: prospective cohort study.Methods: During 3 months duration ( the treatment course duration) , Optical coherence tomography angiography (OCT-A) were imaged to 28 eyes of 28 patients with a documented diagnosis of chronic hepatitis C before and after receiving dual-therapy planning (Daclatasvir- Sofosbuvir ). Results: The results in this study revealed, statistically significant (p-value less than 0.05 %) reduction in the deep capillary plexuses density , and choriocapillaris flow area, and in FAZ flow density (FD ), statistically insignificant reduction in superficial capillary plexuses vessel density and thickness , statistically significant, with appearance of macular drusens and reduction in visual acuity and tear film. Conclusions: HCV Dual treatment (Sofosbuvir, Daclatasvir) may result in significant changes affecting retinal microvasculature and may cause eye dryness |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE |
|---|
| Additional physical form available note |
Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
Daclatasvir |
| 653 #4 - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
Hepatitis C Virus (HCV) |
| 653 #4 - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
Sofosbuvir |
| 700 0# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Daclatasvir , |
| Relator term |
|
| 700 0# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Hany Elmekawey Elmekawey , |
| Relator term |
|
| 700 0# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Magda Salaheldin Abdelaziz Ahmed , |
| Relator term |
|
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) |
|---|
| Cataloger |
Nazla |
| Reviser |
Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) |
|---|
| Cataloger |
Shimaa |
| Reviser |
Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| Source of classification or shelving scheme |
Dewey Decimal Classification |
| Koha item type |
Thesis |
