Assessment of S100 B and CXCL9 as markers of activity in non-segmental vitiligo / (Record no. 78026)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02791cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223032607.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 201003s2020 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | Ph.D |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.11.10.Ph.D.2020.Kh.A |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Kholoud Ahmed Helmy Ahmed |
| 245 10 - TITLE STATEMENT | |
| Title | Assessment of S100 B and CXCL9 as markers of activity in non-segmental vitiligo / |
| Statement of responsibility, etc. | Kholoud Ahmed Helmy Ahmed ; Supervised Doaa Mohamed Aly Mahgoub , Sara Bahaa Eldin Mahmoud , Marwa Ahmed Amer |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | كعلامات للنشاط فى البهاق غير القطعى CXCL9و S100B تقييم |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Kholoud Ahmed Helmy Ahmed , |
| Date of publication, distribution, etc. | 2020 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 121 P. : |
| Other physical details | charts , facsimiles ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Dermatology and Venerology |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Background: Vitiligo is an acquired depigmentary disorder characterized by destruction of melanocytes. The activity of vitiligo influences the clinical outcome and alters the choice of treatment modality. S100B is a calcium binding protein and one of the danger associated molecular patterns. CXCL9 is a chemokine that plays a role in innate defense mechanism. Aim of work: The current study aimed to evaluate the levels of S100B and CXCL9 in patients with non-segmental vitiligo, verify the relationship between both markers and vitiligo activity, and detect the effect of oral minipulse (OMP) steroid therapy on S100B and CXCL9 levels in active non-segmental vitiligo. Patients and methods: This study included 40 non-segmental vitiligo patients (20 patients with active disease and 20 patients with stable vitiligo) and 20 healthy controls. Skin biopsies from the edge of vitiliginous lesions and serum samples were taken from patients. Skin biopsies and serum samples were taken from controls. Enzyme-linked immunosorbent assay (ELISA) test was used to measure tissue and serum S100B, and serum CXCL9 levels. The active vitiligo group received OMP steroids for 6 months, after which clinical examination, skin biopsies and serum samples were taken for assessment of tissue and serum S100B, and serum CXCL9 levels. Results: There was a statistically significant elevation of tissue and serum S100B, as well as serum CXCL9 in vitiligo patients compared to controls |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Activity markers |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | S100B |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Vitiligo |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Doaa Mohamed Aly Mahgoub , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Marwa Ahmed Amer , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Sara Bahaa Eldin Mahmoud , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Shimaa |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.11.10.Ph.D.2020.Kh.A | 01010110081608000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.11.10.Ph.D.2020.Kh.A | 01020110081608000 | 22.09.2023 | CD - Rom | 81608.CD |