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Characterization of the type of response to different HCV antigens and Quantification of viral load in newly diagnosed Hepatocellular Carcinoma patients / (Record no. 78028)

MARC details
000 -LEADER
fixed length control field 02952cam a2200349 a 4500
003 - CONTROL NUMBER IDENTIFIER
control field EG-GiCUC
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20250223032607.0
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 201003s2020 ua dh f m 000 0 eng d
040 ## - CATALOGING SOURCE
Original cataloging agency EG-GiCUC
Language of cataloging eng
Transcribing agency EG-GiCUC
041 0# - LANGUAGE CODE
Language code of text/sound track or separate title eng
049 ## - LOCAL HOLDINGS (OCLC)
Holding library Deposite
097 ## - Thesis Degree
Thesis Level M.Sc
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC)
Classification number Cai01.08.06.M.Sc.2020.Di.C
100 0# - MAIN ENTRY--PERSONAL NAME
Personal name Dina Usama Ahmed Sharaf Eldin
245 10 - TITLE STATEMENT
Title Characterization of the type of response to different HCV antigens and Quantification of viral load in newly diagnosed Hepatocellular Carcinoma patients /
Statement of responsibility, etc. Dina Usama Ahmed Sharaf Eldin ; Supervised Magdy Amin , Hadir Elmahlawy , Samah Radwan
246 15 - VARYING FORM OF TITLE
Title proper/short title توصيف نوع الاستجابة لانتيجينات فيروس (سى) المختلفة وتحديد الحمل الفيروسى فى مرضى سرطان الكبد حديثى التشخيص
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Place of publication, distribution, etc. Cairo :
Name of publisher, distributor, etc. Dina Usama Ahmed Sharaf Eldin ,
Date of publication, distribution, etc. 2020
300 ## - PHYSICAL DESCRIPTION
Extent 73 P. :
Other physical details charts , facsimiles ;
Dimensions 25cm
502 ## - DISSERTATION NOTE
Dissertation note Thesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Microbiology and Immunology
520 ## - SUMMARY, ETC.
Summary, etc. Background: Hepatitis C virus (HCV) is a blood born virus that is considered a major cause of chronic liver disease and hepatocellular carcinoma (HCC) worldwide. HCV is thought to induce HCC either indirectly or directly by the effect of its viral proteins on different host cell proteins and signaling pathways. Objective: The aim of the study was to characterize the type of response to different HCV antigens, quantify HCV viral load, transforming growth factor- beta and miRNA 122 in patients with newly diagnosed Hepatocellular Carcinoma. Patients and methods: This study was done on three groups: the first group consisted of 40 newly discovered hepatocellular carcinoma patients with HCV infection. The second group consisted of twenty HCV infected patients with other types of cancer (other than HCC). The third group consisted of 20 healthy individuals served as a control group. Serum was separated for detection of the four parameters. Results: TGF-Ý showed a very weak negative correlation with the miRNA 122 serum levels that is statistically non-significant. Results also showed that miRNA 122 may not be useful in differentiating between liver cirrhosis from HCC patients and it is associated with the severity of the disease rather than the viremia count.Conclusion: Study showed no correlation between the four investigated parameters (HCV antigens, HCV viral load, TGF-Ý- serum levels of miRNA 122) in an attempt for early diagnosis of HCV induced HCC
530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE
Additional physical form available note Issued also as CD
653 #4 - INDEX TERM--UNCONTROLLED
Uncontrolled term HCV antigens
653 #4 - INDEX TERM--UNCONTROLLED
Uncontrolled term Hepatitis C
653 #4 - INDEX TERM--UNCONTROLLED
Uncontrolled term Hepatocellular Carcinoma
700 0# - ADDED ENTRY--PERSONAL NAME
Personal name Hadir Elmahlawy ,
Relator term
700 0# - ADDED ENTRY--PERSONAL NAME
Personal name Magdy Amin ,
Relator term
700 0# - ADDED ENTRY--PERSONAL NAME
Personal name Samah Radwan ,
Relator term
856 ## - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a>
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN)
Cataloger Nazla
Reviser Revisor
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN)
Cataloger Shimaa
Reviser Cataloger
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme Dewey Decimal Classification
Koha item type Thesis
Holdings
Source of classification or shelving scheme Not for loan Home library Current library Date acquired Full call number Barcode Date last seen Koha item type Copy number
Dewey Decimal Classification   المكتبة المركزبة الجديدة - جامعة القاهرة قاعة الرسائل الجامعية - الدور الاول 11.02.2024 Cai01.08.06.M.Sc.2020.Di.C 01010110081610000 22.09.2023 Thesis  
Dewey Decimal Classification   المكتبة المركزبة الجديدة - جامعة القاهرة مخـــزن الرســائل الجـــامعية - البدروم 11.02.2024 Cai01.08.06.M.Sc.2020.Di.C 01020110081610000 22.09.2023 CD - Rom 81610.CD