Therapy related late effects in pediatric patients with hodgkin lymphoma treated with ABVD protocol at national cancer institute, Cairo University and children cancer ospital Egypt 57357 / (Record no. 78251)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 03616cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223032614.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 201017s2020 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | Ph.D |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.19.05.Ph.D.2020.Mu.T |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Mustafa Mohamed Selim |
| 245 10 - TITLE STATEMENT | |
| Title | Therapy related late effects in pediatric patients with hodgkin lymphoma treated with ABVD protocol at national cancer institute, Cairo University and children cancer ospital Egypt 57357 / |
| Statement of responsibility, etc. | Mustafa Mohamed Selim ; Supervised Mohamed Hani Hussein , Iman Abdelmokhales Sidhom , Zeinab Salah Selim |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | ِِالأثار البعيدة المدى المرتبطة بعلاج الأطفال المصابين بورم هودجكين الغدد الليمفاوية وتم علاجهم ببرتوكول (إيه بى فى دى) فى المعهد القومى للأورام: جامعة القاهرة و مستشفى الأطفال مصر57573 |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Mustafa Mohamed Selim , |
| Date of publication, distribution, etc. | 2020 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 280 P. : |
| Other physical details | charts , facimiles ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (Ph.D.) - Cairo University - National Cancer Institute - Department of Pediatric oncology |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Background/purpose Long-term Hodgkin Lymphoma (HL) survivors are at risk of developing a range of therapy-related complications that may present 10 -15 years after treatment. The primary goal of study is to estimate the frequency of late effects and to determine risk factors that may contribute to this. Methods We performed a cross-sectional study on HL survivors{u2019} who were treated at National Cancer Institute, Cairo or Children Cancer Hospital Egypt 57357 with ABVD chemotherapy ± radiotherapy with a minimum 5 years follow up. Results Two hundred and eight patients were candidate. The cumulative incidence (CI) of cardiac toxicity (CT) at 5 and 9 years was 18.7% ± SD 2.7 and 43.3% ± SD 4.4, respectively. Preexisting cardiac abnormalities, cumulative anthracycline dose and end of treatment cardiac status are a strong predictor for late cardiotoxicity. Hypertension, was observed in about 31% of HL survivors. Young age (prepuberty) and obesity at time of treatment are important factors for hypertension. Thyroid abnormalities developed with a 5-year CI of 2% (95% CI 0.6% - 4.9%) while at 9-years the CI was 27.9% (95% CI 19% - 36%). Neck radiation therapy and the percentage of thyroid gland exposed to radiation are important risk factors.Obesity, was observed in 36% of HL survivors. High body mass index and older age (post-puberty) at the initial presentation are significant factors for obesity during the follow up. Endocrine hypogonadism was present in 22.5% of male survivors and 38% of female survivors. Disturbance of menstrual cycles was XII present in about one-third of female survivors. Furthermore, exposure to radiation therapy was associated with higher risk of irregular menstrual cycles. Abnormal pulmonary function tests were found in 43% and restrictive pattern was the most common type. Secondary cancers were founded in 3 patients (1.4%) |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Doxorubicin, bleomycin, vinblastine, and dacarbazine (ABVD) |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Hodgkin Lymphoma survivors |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Late effects |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Iman Abdelmokhales Sidhom , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mohamed Hani Hussein , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Zeinab Salah Selim , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Shimaa |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.19.05.Ph.D.2020.Mu.T | 01010110081746000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.19.05.Ph.D.2020.Mu.T | 01020110081746000 | 22.09.2023 | CD - Rom | 81746.CD |