Mannose binding lectin gene polymorphism versus microbial virulence in the pathogenesis of vulvovaginal candidiasis / (Record no. 78331)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 03095cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223032616.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 201019s2020 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | Ph.D |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.11.19.Ph.D.2020.Em.M |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Eman Mohammed Mohammed Hamed Haggag |
| 245 10 - TITLE STATEMENT | |
| Title | Mannose binding lectin gene polymorphism versus microbial virulence in the pathogenesis of vulvovaginal candidiasis / |
| Statement of responsibility, etc. | Eman Mohammed Mohammed Hamed Haggag ; Supervised Iman Ezzat Wali , Alaa Mohammed Reda Awad , Mohammed Abdelaziz Elsharkawy |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | تعدد شكل جين سكر المانوز المرتبط بالليكتين مقابل فوعية الميكروبات في تولد مرض داء المبيضات الفرجى المهبلى |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Eman Mohammed Mohammed Hamed Haggag , |
| Date of publication, distribution, etc. | 2020 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 156 P. : |
| Other physical details | charts , facsimiles ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Microbiology and Immunology |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Vulvovaginal candidiasis (VVC) remains one of the most common infections of the female genital tract affecting millions of women every year. The current study was designed to determine the frequency of MBL2 gene polymorphism among Egyptian females with vulvovaginal candidiasis and to assess the role of Candida virulence attributes together with host genetic polymorphism in the pathogenesis of such a condition. The study population included 50 cases with vulvovaginal candidiasisand another 50 controls. Vaginal swabs were cultured and species identification was done. MBL2polymorphism in both cases and controls was determined by double amplification refractory mutation system (D-ARMs) from blood sample. Among the different risk factors that were compared between cases and controls, contraception and antifungal use were more in cases than controls, but only antifungals showed almost statistically significant difference between cases and controls (P value = 0.059).There was a statistically significant difference between C. albicans and non albicansCandida (NAC) esterase and phospholipase (P value <0.001).Thirty C. albicans isolates (81.1%) possessed three or more virulence factors, compared to only four NAC (30.8%) with statistically significant difference (P value = 0.002). As regards MBL2 polymorphism, the frequency of X allele was found to be significantly high in cases as compared to controls (P value {u2264} 0.001). B allele on codon 54 and L allele on promoter region were also more among cases than controls |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Candida species |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Candida virulence factors |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | MBL₂ polymorphisms Vulvovaginal Candidiasis |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Alaa Mohammed Reda Awad , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Iman Ezzat Wali , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mohammed Abdelaziz Elsharkawy , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Shimaa |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.11.19.Ph.D.2020.Em.M | 01010110081778000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.11.19.Ph.D.2020.Em.M | 01020110081778000 | 22.09.2023 | CD - Rom | 81778.CD |