Development and validation of different analytical methods for determination of some drugs used for the treatment of GIT diseases / (Record no. 78677)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02377cam a2200337 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223032627.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 201110s2020 ua d f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | Ph.D |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.08.05.Ph.D.2020.Me.D |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Mennatallah Ismail Ezz Eldin |
| 245 10 - TITLE STATEMENT | |
| Title | Development and validation of different analytical methods for determination of some drugs used for the treatment of GIT diseases / |
| Statement of responsibility, etc. | Mennatallah Ismail Ezz Eldin ; Supervised Marwa Ahmed Fouad , Ramzia Ismail Elbagary |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | تطوير و تقييم طرق تحليلية مختلفة لتقدير بعض الأدوية المستخدمة فى علاج أمراض الجهاز الهضمى |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Mennatallah Ismail Ezz Eldin , |
| Date of publication, distribution, etc. | 2020 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 282 P . : |
| Other physical details | charts , facsmilies ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (Ph.D.) - Cairo University - Faculty of Pharmacy - Department of Pharmaceutical Chemistry |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Different methods for the determination of some drugs used for the treatment of GIT diseases, in bulk, dosage forms and in rat liver homogenate have been introduced in this thesis. These drugs are aprepitant, fosaprepitant, ondansetron, palonosetron, tropisetron, omeprazole, pantoprazole and ranitidine. Chromatographic part includes UPLC determination of some mixtures namely a binary mixture of ondansetron and omeprazole in pharmaceutical dosage form, a ternary mixture of ondansetron, pantoprazole and ranitidine in two combined dosage forms. In addition, a validated UPLC method was developed for the determination of aprepitant and its prodrug fosaprepitant and applied to an in-vitro activation of prodrug fosaprepitant to the active drug aprepitant using liver S9 fraction. Spectroscopic part includes two quantitative nuclear magnetic resonance spectroscopic (QNMR) methods for the determination of ondansetron (OND) and omeprazole (OMP) in bulk drugs and theirpharmaceutical dosage forms |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Aprepitant |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Fosaprepitant |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Ondansetron |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Marwa Ahmed Fouad , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ramzia Ismail Elbagary , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Amira |
| Reviser | Cataloger |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.08.05.Ph.D.2020.Me.D | 01010110081990000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.08.05.Ph.D.2020.Me.D | 01020110081990000 | 22.09.2023 | CD - Rom | 81990.CD |