Effects of treadmill exercise compared to metformin on insulin resistance and biomarkers of Alzheimer's disease in streptozotocin-induced diabetic rats / (Record no. 78693)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02929cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223032627.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 201112s2018 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | Ph.D |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.11.30.Ph.D.2018.Mo.E |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Mohammed Abdou Amin |
| 245 10 - TITLE STATEMENT | |
| Title | Effects of treadmill exercise compared to metformin on insulin resistance and biomarkers of Alzheimer's disease in streptozotocin-induced diabetic rats / |
| Statement of responsibility, etc. | Mohammed Abdou Amin ; Supervised Akef Abdelhalim Khowailed , Laila Ahmed Rashed , Hader Ibrahim Sakr |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | تأثير ممارسة الجري مقارنة مع ميتفورمين علي مقاومة الانسولين و الدلالات البيولوجية لمرض الزهايمر فى الفئران المصابة بداء السكرى عن طريق عقار الستريبتوزوتوسين |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Mohammed Abdou Amin , |
| Date of publication, distribution, etc. | 2018 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 169 P. : |
| Other physical details | charts , facsmilies ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Physiology |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | T2D and AD are two major health issues that are belived to have common features that link both diseases to the limit that AD is now considered type 3 diabetes. The aim of this study was to compare the effect of aerobic treadmill exercise on the insulin resistance and biomarkers of Alzheimer's disease to those effects exerted by metformin treatment in diabetic rats. In this work four groups of experimental animals were formed of ten rats including: control group, diabetic sedentary non-treated group, diabetic exercised group and a diabetic metformin treated group. For each group serum glucose, insulin, free fatty acids, total cholesterol, HDL, LDL and triglycerides, brain AÝ42 and glucose, latency of step-down avoidance task (2 hour and 48 hour after training) and finally immunohistochemistry for brain AÝ42 and tau positive cells were estimated. Diabetes had led to significant increase in serum glucose, FFA, TG, Cholesterol, LDL, Brain AÝ42, brain glucose and brain AÝ42 and tau positive cells and causedsignificant decrease in serum insulin, serum HDL and latency of step-down avoidance task (2 hours and 48 hours after training). Treadmill exercise caused a significant decrease in serum glucose, serum FFA, TG, cholesterol, LDL, brain glucose, brain AÝ42, brain AÝ42 and tau positive cells and a significant increase in serum insulin |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Alzheimer's disease |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Diabetes |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Treadmill exercise |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Akef Abdelhalim Khowailed , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Hader Ibrahim Sakr , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Laila Ahmed Rashed , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Amira |
| Reviser | Cataloger |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.11.30.Ph.D.2018.Mo.E | 01010110081991000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.11.30.Ph.D.2018.Mo.E | 01020110081991000 | 22.09.2023 | CD - Rom | 81991.CD |