Formulation, physico-chemical characterization and evaluation of biological performance of folic acid in nanostructured lipid carriers / (Record no. 78960)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 03179cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223032636.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 201124s2020 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | Ph.D |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.08.10.Ph.D.2020.Em.F |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Eman Samy Ibrahim Shalaby |
| 245 10 - TITLE STATEMENT | |
| Title | Formulation, physico-chemical characterization and evaluation of biological performance of folic acid in nanostructured lipid carriers / |
| Statement of responsibility, etc. | Eman Samy Ibrahim Shalaby ; Supervised Mahmoud M. Ghorab , Hussein O. Ammar , Salwa M. Salah Eldin |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | صياغة و توصيف فيزيائى كيميائى و تقييم الأداء البيولوجى لحاملات دهنية نانومترية لحمض الفوليك |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Eman Samy Ibrahim Shalaby , |
| Date of publication, distribution, etc. | 2020 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 168 P . : |
| Other physical details | charts ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (Ph.D.) - Cairo University - Faculty of Pharmacy - Department of Industrial Pharmacy |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Using Folic acid (FA), also named vitamin B9, in treating skin photoaging seems promising as it plays a role in cell replication, regulation of gene activity and renewal of skin. FA is available in natural and synthetic forms. FA is an antioxidant so stops and protects from excessive radiation. It is of importance in rapidly dividing cells. The photoaging results from excessive exposure to UV- irradiation which in turn results in excessive oxidation. Treatment of cultured dermal fibroblasts with folic acid stimulated cellular DNA repair capacity, indicating that this essential vitamin may offer a treatment option for photo-aged skin. Bearing hydrophobic character, the upper layer of the skin and the stratum corneum would be amended by FA in personal care and cosmetic products. Folic acid belongs to a group of highly effective actives that elicits a variety of beneficial actions on human skin. Folic acid is firstly suggested as a cosmetic ingredient in patents of a topical cream in the nineties and later on. Additionally it was presented by debowska et al as a study on human cell lines in 2005. Also, it was included in multi herbal cream in 2013 to work synergistically with other herbs to soothe, moisturize, heal, and regenerate skin. That cream also provided anti-wrinkle and sunscreen effect.The discovery of the link between insufficient folic acid intake and the incidence of neural tube defects emphasizes that an adequate folate status is essential to guarantee normal development and growth. With regard to the skin, it was published earlier that human dermal fibroblasts increase their intracellular folate levels when exposed to UV irradiation provided that sufficient amounts of folic acid are supplied externally |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Antioxidant |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Folic acid |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Nanostructured lipid carriers |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Hussein O. Ammar, |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mahmoud M. Ghorab , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Salwa M. Salah Eldin , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Amira |
| Reviser | Cataloger |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.08.10.Ph.D.2020.Em.F | 01010110082172000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.08.10.Ph.D.2020.Em.F | 01020110082172000 | 22.09.2023 | CD - Rom | 82172.CD |