Formulation and evaluation of a model drug in certain ear drug delivery systems / (Record no. 78996)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02477cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223032637.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 201129s2020 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | Ph.D |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.08.08.Ph.D.2020.Ra.F |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Raghda Rabe Mohammed Mohammed Hamed |
| 245 10 - TITLE STATEMENT | |
| Title | Formulation and evaluation of a model drug in certain ear drug delivery systems / |
| Statement of responsibility, etc. | Raghda Rabe M.Mohammed Hamed ; Supervised Mohamed Farid Elmiligi , Mohamed Ahmed Elnabarawi , Sally Adel Abdelhalim |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | صياغه وتقييم نموذج عقار فى بعض انظمه التوصيل الدوائى عبر الاذن |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Raghda Rabe Mohammed Mohammed Hamed , |
| Date of publication, distribution, etc. | 2020 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 136 P. : |
| Other physical details | charts , facsmilies ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (Ph.D.) - Cairo University - Faculty of Pharmacy - Department of Pharmaceutics |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Cinnarizine is indicated orally as tablets of 25 and 75mg for the treatment of vertigo, tinnitus, hearing loss and nausea associated with Ménière's syndrome. It has a local anaesthetic effect in addition to its ability to manage cerebrovascular insufficiency, cases of memory reduction and migraine. However, Cinnarizine is highly metabolized primarily by the liver. The present study aims to develop an aural Cinnarizine mucoadhesive transfersomal gel that overcomes the liver first pass metabolic effect. The gel form provides a targeted and suitable residence of the Cinnarizine Transfersomes over the tympanic membrane; the elastic vesicles can pass through the intact tympanic membrane to the middle ear then into the systemic circulation. The work in this thesis is divided into three chapters, namely: Chapter I: Formulation and evaluation of Cinnarizine nano- Transfersomes. Chapter II: Formulation and evaluation of Cinnarizine Transfersomes into aural mucoadhesive gel delivery systems. Chapter III: A Pharmacokinetic study of Cinnarizine aural transfersomal gel on rabbits. |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Cinnarizine |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Phosphatidylcholine |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Soya phosphatidylcholine |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mohamed Ahmed Elnabarawi , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mohamed Farid Elmiligi , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Sally Adel Abdelhalim , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Amira |
| Reviser | Cataloger |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.08.08.Ph.D.2020.Ra.F | 01010110082176000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.08.08.Ph.D.2020.Ra.F | 01020110082176000 | 22.09.2023 | CD - Rom | 82176.CD |