Radio mitigation of acute radiation induced normal tissue injury using spirulina / (Record no. 79091)
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000 -LEADER | |
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fixed length control field | 02945cam a2200337 a 4500 |
003 - CONTROL NUMBER IDENTIFIER | |
control field | EG-GiCUC |
005 - DATE AND TIME OF LATEST TRANSACTION | |
control field | 20250223032640.0 |
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
fixed length control field | 201205s2020 ua dh f m 000 0 eng d |
040 ## - CATALOGING SOURCE | |
Original cataloging agency | EG-GiCUC |
Language of cataloging | eng |
Transcribing agency | EG-GiCUC |
041 0# - LANGUAGE CODE | |
Language code of text/sound track or separate title | eng |
049 ## - LOCAL HOLDINGS (OCLC) | |
Holding library | Deposite |
097 ## - Thesis Degree | |
Thesis Level | Ph.D |
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
Classification number | Cai01.12.04.Ph.D.2020.Al.R |
100 0# - MAIN ENTRY--PERSONAL NAME | |
Personal name | Aliaa Alaa Eldin Abdelhamid Mazhar |
245 10 - TITLE STATEMENT | |
Title | Radio mitigation of acute radiation induced normal tissue injury using spirulina / |
Statement of responsibility, etc. | Aliaa Alaa Eldin Abdelhamid Mazhar ; Supervised Wafaa Khalil , Aisha Ahmed Saad Eldin |
246 15 - VARYING FORM OF TITLE | |
Title proper/short title | التخفيف من إصابة الأنسجة الطبيعية الناجمة عن التأثير الحاد من الإشعاع باستخدام السبيرولينا |
260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
Place of publication, distribution, etc. | Cairo : |
Name of publisher, distributor, etc. | Aliaa Alaa Eldin Abdelhamid Mazhar , |
Date of publication, distribution, etc. | 2020 |
300 ## - PHYSICAL DESCRIPTION | |
Extent | 145 P. : |
Other physical details | charts , facsimiles ; |
Dimensions | 25cm |
502 ## - DISSERTATION NOTE | |
Dissertation note | Thesis (Ph.D.) - Cairo University - Faculty of Science - Department of Biophysics |
520 ## - SUMMARY, ETC. | |
Summary, etc. | There was significant (P{u2264}0.05) increase in the peaks absorbance for glycogen, phospholipid and polysccharide/glycogen deformation in liver for group (4Gy). Spirulina given before or after gamma irradiation ameliorates these changes. The liver secondary structure of Amide I for 4Gy, showed decrease in Ý - additional and increase in Ü-helix. These changes were repaired by giving spirulina before or after irradiation. For lyophilized Hb there was increase in both Amide A & Amide B absorbance in the secondary amide region for irradiated group. While in the amides region there was non-significant increase in Amide I and significant increase in Amide IV (Tyrosine) and Amide VIII phosphate stretching band. Spirulina ameliorated these changes. Spirulina given before or after gamma irradiation ameliorates the increase in Ý-sheet & the decrease of Ü-helix in Amide I secondary structure. Principle component analysis (PCA) for the FTIR-ATR spectra of all animal groups for the different tissues, demonstrated a cluster of the irradiated group while rest of the groups clustered together. This indicates different molecular changes for the irradiated group other than the rest of the groups. Electron Spin Resonance (ESR) of lyophilized brain, liver and blood tissue indicated increase in the free radicals for 4Gy. Spirulina given before or after gamma irradiation have a free radical scavenging role in brain, liver and blood. We conclude that spirulina ameliorates the damage occurred in white matter than that in grey matter. And it has a protective and curative effect for both liver and Hb/Blood |
530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
Additional physical form available note | Issued also as CD |
653 #4 - INDEX TERM--UNCONTROLLED | |
Uncontrolled term | Gamma irradiation |
653 #4 - INDEX TERM--UNCONTROLLED | |
Uncontrolled term | Radio mitigation |
653 #4 - INDEX TERM--UNCONTROLLED | |
Uncontrolled term | Spirulina |
700 0# - ADDED ENTRY--PERSONAL NAME | |
Personal name | Aisha Ahmed Saad Eldin , |
Relator term | |
700 0# - ADDED ENTRY--PERSONAL NAME | |
Personal name | Wafaa Khalil , |
Relator term | |
856 ## - ELECTRONIC LOCATION AND ACCESS | |
Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
Cataloger | Nazla |
Reviser | Revisor |
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
Cataloger | Shimaa |
Reviser | Cataloger |
942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
Source of classification or shelving scheme | Dewey Decimal Classification |
Koha item type | Thesis |
Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
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Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.12.04.Ph.D.2020.Al.R | 01010110082250000 | 22.09.2023 | Thesis | ||
Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.12.04.Ph.D.2020.Al.R | 01020110082250000 | 22.09.2023 | CD - Rom | 82250.CD |