Metaproteomics study of autism spectral disorder in pediatric patients : (Record no. 79437)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02820cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223032651.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 210103s2020 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.12.25.M.Sc.2020.Ay.M |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Aya Osama Fekry Ibrahim Khamis |
| 245 10 - TITLE STATEMENT | |
| Title | Metaproteomics study of autism spectral disorder in pediatric patients : |
| Remainder of title | potential clinical impact / |
| Statement of responsibility, etc. | Aya Osama Fekry Ibrahim Khamis ; Supervised Ismail Abdelshafy Abdelhamid , Sherif Abdelaziz Ibrahim , Sameh Magdeldin Mohamed |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | الآثار السريرية المحتملة : |
| Remainder of title | دراسة الميتابروتيومكس الخاص بالأطفال المرضى بالتوحد |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Aya Osama Fekry Ibrahim Khamis , |
| Date of publication, distribution, etc. | 2020 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 116 P . : |
| Other physical details | charts , facsmilies ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (M.Sc.) - Cairo University - Faculty of Science - Department of Biotechnology |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | ASD (Autism Spectrum Disorder) is a class of neurodevelopmental disorders that affects communication and behavior. The prevalence of these pervasive disorders has been estimated to be as high as 1 in every 45 individuals. Gastrointestinal (GI) symptoms are common disorders associated with ASD patients, however, the underlying mechanisms are still unknown. Many studies have shown alterations in the composition of the fecal flora of the gut microbiome in patients with ASD. The gut microbiota has been proposed to influences brain development and behaviors through the neuroendocrine, neuroimmune, and autonomic nervous systems. Additionally, abnormal gut microbiota was reported to be associated with several diseases, such as inflammatory bowel disease (IBD), ASD, and mood disorders. Recent research proposed that toxins produced by abnormal gut bacteria may trigger or worsen autism in some children. It is thought that these molecular signals largely originate from the microbiome and they play a crucial role in basic neurodegenerative processes such as affecting the permeability of blood-brain-barrier, myelination, neurogenesis, microglia maturation, and also modulates many aspects of animal behavior. Thus, focused analysis on the metaproteome of ASD patients together with host proteome interaction will provide new insights in understanding the role of the gut microbiota in the ASD |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | ASD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Metaproteome |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Microbiota |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ismail Abdelshafy Abdelhamid , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Sameh Magdeldin Mohamed , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Sherif Abdelaziz Ibrahim , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Amira |
| Reviser | Cataloger |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.12.25.M.Sc.2020.Ay.M | 01010110082463000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.12.25.M.Sc.2020.Ay.M | 01020110082463000 | 22.09.2023 | CD - Rom | 82463.CD |