Phytochemical and biological investigation of averrhoa carambola L. (Family : Oxalidaceae) cultivated in Egypt / (Record no. 79652)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 03550cam a2200325 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 210123s2020 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | Ph.D |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.08.07.Ph.D.2020.Ne.P |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Nehal Sameh Mohammed Ramadan |
| 245 10 - TITLE STATEMENT | |
| Title | Phytochemical and biological investigation of averrhoa carambola L. (Family : Oxalidaceae) cultivated in Egypt / |
| Statement of responsibility, etc. | Nehal Sameh Mohammed Ramadan ; Supervised Mohamed Ali Ali Farag , Nabil Hussein Elsayed Khamis , Zeinab Kandil |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | دراسة فيتوكيميائية و بيولوجية لنبات برتقال البامية (العائلة الحماضية) المزروع فى مصر |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Nehal Sameh Mohammed Ramadan , |
| Date of publication, distribution, etc. | 2020 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 314 P. : |
| Other physical details | charts , facimiles ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (Ph.D.) - Cairo University - Faculty of Pharmacy - Department of Pharmacognosy |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Averrhoa carambola L. is a tropical tree with edible fruits that grows at different climatic conditions. Despite its nutritive value and reported health benefits, it is a controversial plant owing to its fruits rich oxalate content.The present study aimed at investigating aroma and nutrient primary metabolites distribution in A. carambola fruits grown in Indonesia, Malaysia (its endemic origin) versus Egypt, and at different ripening stages.Two techniques were employed to assess for volatile and non-volatile metabolites including headspace solid-phase micro-extraction (HS-SPME) coupled to gas chromatography mass-spectrometry (GC-MS) and GC-MS post silylation, respectively. 24Volatiles were detected, with esters amounting for the major class in Egyptian fruits at ca. 66%, with methyl caproate as the major component. Primary metabolites profiling led to the identification of 117 metabolites viz. sugars, polyols and organic acids. Fructose (38{u2013}48%) and glucose (21{u2013}25%) predominated sugar compositions in ripe fruits, whereas sorbitol was the major sugar alcohol (2.4{u2013}10.5%) in ripe fruits as well. Oxalic acid, an anti-nutrient with potential health risks, was the major organic acid detected in all fruits (1.7{u2013}2.7%), except the Malaysian one (0.07%). Further objective of this study was to investigate the use of its plant parts (leaves & fruits) cultivated in Egypt forthe treatment of obesity as extracts and its isolated compounds.The effect of the total MeOHextracts of leaf and fruit on high-fat diet induced obesity in rats was evaluated in vivo. Results revealed thatboth extracts exhibited potential anti-obese activity in comparison to Orly as a reference drug. To pinpoint for the active agents in A. carambolaleaf extract cultivated in Egypt as an anti-obese and antidiabetic agents,a detailed phytochemical study was adopted. 14 compounds were isolated including 3 new dihydrochalcone glycosides & 1 flavonoid glycoside. The isolated compounds were comparatively assessed for their antidiabetic and cytotoxic activities. Structure-activity relationship (SAR) was adopted to determine the effect of substitution pattern on biological effects |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | A. carambola |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Anti-obesity |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Cytotoxicity |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mohamed Ali Ali Farag , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Nabil Hussein Elsayed Khamis , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Zeinab Kandil , |
| Relator term | |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Shimaa |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.08.07.Ph.D.2020.Ne.P | 01010110082614000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.08.07.Ph.D.2020.Ne.P | 01020110082614000 | 22.09.2023 | CD - Rom | 82614.CD |