MARC details
000 -LEADER |
fixed length control field |
03576cam a2200325 a 4500 |
003 - CONTROL NUMBER IDENTIFIER |
control field |
EG-GiCUC |
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
fixed length control field |
210130s2020 ua dh f m 000 0 eng d |
040 ## - CATALOGING SOURCE |
Original cataloging agency |
EG-GiCUC |
Language of cataloging |
eng |
Transcribing agency |
EG-GiCUC |
041 0# - LANGUAGE CODE |
Language code of text/sound track or separate title |
eng |
049 ## - LOCAL HOLDINGS (OCLC) |
Holding library |
Deposite |
097 ## - Thesis Degree |
Thesis Level |
M.Sc |
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
Classification number |
Cai01.11.18.M.Sc.2020.Al.S |
100 0# - MAIN ENTRY--PERSONAL NAME |
Personal name |
Alaa Mohammed AlSayed Mohammed |
245 10 - TITLE STATEMENT |
Title |
Silent thrombosis detected by duplex in patients with lymphoproliferative disorders and its relation to anti phospholipid antibodies / |
Statement of responsibility, etc. |
Alaa Mohammed Alsayed Mohammed ; Supervised Mervat Mohamed Mattar , Sahar Nassef , Mohammed Abdelkader Mourad |
246 15 - VARYING FORM OF TITLE |
Title proper/short title |
دراسة تجلط الدم الصامت الذى يتم اكتشافه عن طريق استخدامات الموجات الصوتيه على الأوعية الدموية فى مرضى الأضطرابات التكاثرية اللمفاوية وعلاقته بالأجسام المضادة للفوسفوليبيد |
260 ## - PUBLICATION, DISTRIBUTION, ETC. |
Place of publication, distribution, etc. |
Cairo : |
Name of publisher, distributor, etc. |
Alaa Mohammed Alsayed Mohammed , |
Date of publication, distribution, etc. |
2020 |
300 ## - PHYSICAL DESCRIPTION |
Extent |
146 P. : |
Other physical details |
charts , facimiles ; |
Dimensions |
25cm |
502 ## - DISSERTATION NOTE |
Dissertation note |
Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Internal Medicine |
520 ## - SUMMARY, ETC. |
Summary, etc. |
Rationale: Lymphoproliferative disorders consist of a heterogeneous group of disorders that are characterized by an autonomous, uncontrolled proliferation of lymphoid cells that cause monoclonal lymphocytosis, lymphadenopathy and bone marrow infiltration. Antiphospholipid antibodies (aPL) are a heterogeneous group of autoantibodies reacting against phospholipids, phospholipid-protein complexes and phospholipid binding proteins, detected by different assays: lupus anticoagulant (LA), anticardiolipin (aCL) and anti-Ý2 glycoprotein I (anti-Ý2GPI) antibodies.The coincidence of malignancies and the presence of aPL has been described in many important epidemiological studies. Several studies showed that hematological and lymphoproliferative malignancies, may indeed be associated with the generation of aPL but do not necessarily increase the risk of thrombosis in these patients. Purpose: This study aims to evaluate the association of lymphoproliferative disorders and thrombosis -evident by duplex- in clinically asymptomatic patients.These results are then compared to antiphospholipid antibodies (LAC, ACL and anti- B2glycoprotein I) to detect if there is an association between thrombosis and APL. If a relation is established, APL could be used in the future as a screening tool for thrombosis risk in LPD patients. Methodology: Our study was conducted on 46 patients of lymphoproliferative disorders diagnosed by either lymph node biopsy or bone marrow aspirate and biopsy and immunophenotyping. Patients were recruited from Kasr Alainy clinical hematology department in the period from 2019 to 2020. These patients performed duplex on mesenteric and lower limb vessels to detect recent thrombosis or evidence of old thrombotic events. The patients were also investigated for PTT, LA and antibodies of B2glycoprotein I and anticardiolipin by Enzyme Linked Immune Sorbent Assay (ELISA) technique and other tests were done including CBC, liver function tests, renal function tests, LDH and coagulation profile |
530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE |
Additional physical form available note |
Issued also as CD |
653 #4 - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
Anticardiolipin (aCL) |
653 #4 - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
Lymphoproliferative |
653 #4 - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
Phospholipid |
700 0# - ADDED ENTRY--PERSONAL NAME |
Personal name |
Mervat Mohamed Mattar , |
Relator term |
|
700 0# - ADDED ENTRY--PERSONAL NAME |
Personal name |
Mohammed Abdelkader Mourad , |
Relator term |
|
700 0# - ADDED ENTRY--PERSONAL NAME |
Personal name |
Sahar Nassef , |
Relator term |
|
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) |
Cataloger |
Nazla |
Reviser |
Revisor |
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) |
Cataloger |
Shimaa |
Reviser |
Cataloger |
942 ## - ADDED ENTRY ELEMENTS (KOHA) |
Source of classification or shelving scheme |
Dewey Decimal Classification |
Koha item type |
Thesis |