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Silent thrombosis detected by duplex in patients with lymphoproliferative disorders and its relation to anti phospholipid antibodies / (Record no. 79735)

MARC details
000 -LEADER
fixed length control field 03576cam a2200325 a 4500
003 - CONTROL NUMBER IDENTIFIER
control field EG-GiCUC
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 210130s2020 ua dh f m 000 0 eng d
040 ## - CATALOGING SOURCE
Original cataloging agency EG-GiCUC
Language of cataloging eng
Transcribing agency EG-GiCUC
041 0# - LANGUAGE CODE
Language code of text/sound track or separate title eng
049 ## - LOCAL HOLDINGS (OCLC)
Holding library Deposite
097 ## - Thesis Degree
Thesis Level M.Sc
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC)
Classification number Cai01.11.18.M.Sc.2020.Al.S
100 0# - MAIN ENTRY--PERSONAL NAME
Personal name Alaa Mohammed AlSayed Mohammed
245 10 - TITLE STATEMENT
Title Silent thrombosis detected by duplex in patients with lymphoproliferative disorders and its relation to anti phospholipid antibodies /
Statement of responsibility, etc. Alaa Mohammed Alsayed Mohammed ; Supervised Mervat Mohamed Mattar , Sahar Nassef , Mohammed Abdelkader Mourad
246 15 - VARYING FORM OF TITLE
Title proper/short title دراسة تجلط الدم الصامت الذى يتم اكتشافه عن طريق استخدامات الموجات الصوتيه على الأوعية الدموية فى مرضى الأضطرابات التكاثرية اللمفاوية وعلاقته بالأجسام المضادة للفوسفوليبيد
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Place of publication, distribution, etc. Cairo :
Name of publisher, distributor, etc. Alaa Mohammed Alsayed Mohammed ,
Date of publication, distribution, etc. 2020
300 ## - PHYSICAL DESCRIPTION
Extent 146 P. :
Other physical details charts , facimiles ;
Dimensions 25cm
502 ## - DISSERTATION NOTE
Dissertation note Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Internal Medicine
520 ## - SUMMARY, ETC.
Summary, etc. Rationale: Lymphoproliferative disorders consist of a heterogeneous group of disorders that are characterized by an autonomous, uncontrolled proliferation of lymphoid cells that cause monoclonal lymphocytosis, lymphadenopathy and bone marrow infiltration. Antiphospholipid antibodies (aPL) are a heterogeneous group of autoantibodies reacting against phospholipids, phospholipid-protein complexes and phospholipid binding proteins, detected by different assays: lupus anticoagulant (LA), anticardiolipin (aCL) and anti-Ý2 glycoprotein I (anti-Ý2GPI) antibodies.The coincidence of malignancies and the presence of aPL has been described in many important epidemiological studies. Several studies showed that hematological and lymphoproliferative malignancies, may indeed be associated with the generation of aPL but do not necessarily increase the risk of thrombosis in these patients. Purpose: This study aims to evaluate the association of lymphoproliferative disorders and thrombosis -evident by duplex- in clinically asymptomatic patients.These results are then compared to antiphospholipid antibodies (LAC, ACL and anti- B2glycoprotein I) to detect if there is an association between thrombosis and APL. If a relation is established, APL could be used in the future as a screening tool for thrombosis risk in LPD patients. Methodology: Our study was conducted on 46 patients of lymphoproliferative disorders diagnosed by either lymph node biopsy or bone marrow aspirate and biopsy and immunophenotyping. Patients were recruited from Kasr Alainy clinical hematology department in the period from 2019 to 2020. These patients performed duplex on mesenteric and lower limb vessels to detect recent thrombosis or evidence of old thrombotic events. The patients were also investigated for PTT, LA and antibodies of B2glycoprotein I and anticardiolipin by Enzyme Linked Immune Sorbent Assay (ELISA) technique and other tests were done including CBC, liver function tests, renal function tests, LDH and coagulation profile
530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE
Additional physical form available note Issued also as CD
653 #4 - INDEX TERM--UNCONTROLLED
Uncontrolled term Anticardiolipin (aCL)
653 #4 - INDEX TERM--UNCONTROLLED
Uncontrolled term Lymphoproliferative
653 #4 - INDEX TERM--UNCONTROLLED
Uncontrolled term Phospholipid
700 0# - ADDED ENTRY--PERSONAL NAME
Personal name Mervat Mohamed Mattar ,
Relator term
700 0# - ADDED ENTRY--PERSONAL NAME
Personal name Mohammed Abdelkader Mourad ,
Relator term
700 0# - ADDED ENTRY--PERSONAL NAME
Personal name Sahar Nassef ,
Relator term
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN)
Cataloger Nazla
Reviser Revisor
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN)
Cataloger Shimaa
Reviser Cataloger
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme Dewey Decimal Classification
Koha item type Thesis
Holdings
Source of classification or shelving scheme Not for loan Home library Current library Date acquired Full call number Barcode Date last seen Koha item type Copy number
Dewey Decimal Classification   المكتبة المركزبة الجديدة - جامعة القاهرة قاعة الرسائل الجامعية - الدور الاول 11.02.2024 Cai01.11.18.M.Sc.2020.Al.S 01010110082654000 22.09.2023 Thesis  
Dewey Decimal Classification   المكتبة المركزبة الجديدة - جامعة القاهرة مخـــزن الرســائل الجـــامعية - البدروم 11.02.2024 Cai01.11.18.M.Sc.2020.Al.S 01020110082654000 22.09.2023 CD - Rom 82654.CD