Diversity and bioactivity assessment of microbial endophytes associated calotropis procera plant in petrified forest protected area / (Record no. 79820)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 03066cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223032702.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 210207s2020 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.12.18.M.Sc.2020.Ah.D |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Ahmed Mohamed Ali Mohamed |
| 245 10 - TITLE STATEMENT | |
| Title | Diversity and bioactivity assessment of microbial endophytes associated calotropis procera plant in petrified forest protected area / |
| Statement of responsibility, etc. | Ahmed Mohamed Ali Mohamed ; Supervised Tahany Mohamed Abdelrahman , Mohamed Gamal Farahat , Ahmed Atef Elbeih |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | تقييم التنوع والنشاط الحيوى للميكروبات الداخلية المصاحبة لنبات العشار فى محمية الغابة المتحجرة |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Ahmed Mohamed Ali Mohamed , |
| Date of publication, distribution, etc. | 2020 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 152 P. : |
| Other physical details | charts , facimiles ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (M.Sc.) - Cairo University - Faculty of Science - Department of Microbiology |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | The discovery and production of novel bioactive compounds from natural sources is the target of several studies to combat the emergence of multidrug resistant pathogens. Calotropis procera plant was collected from petrified forest protected area located at El Qattameya, New Cairo, Egypt. In the present study, 50 endophytic microorganisms (8 fungal isolates and 42 bacterial isolates) isolated from C. procera plant and screened for their antimicrobial and antioxidant activities. The bioactive endophytes were selected for phenotypic and molecular identification. Among all isolated endophytes, Aspergillus ochraceus strain CPE7 showed the highest antimicrobial and antioxidant activities was selected for further investigations.The crude extract of A. ochraceus was subjected to chromatographic and spectroscopic techniques to purify the bioactive compounds and elucidate their chemical structures.This led to identification of butyrolactone 1 (BL-1) as bioactive compound. BL-1 exhibited antibacterial activity against Staphylococcus aureus, Bacillus subtilis and Micrococcus luteus with MICs 32, 128 and 64 og/ml, respectively. But no activity was observed against Escherichia coli and Salmonella typhi. Furthermore, BL-1 exhibited high antioxidant activity against DPPH. In the in vivo study, silkworm larvae were used as model organism, which declared that BL-1 exhibited no cytotoxicity up to concentration 48 mg/ml. It also protected silkworms against the pathogenic bacteria S. aureus. So, bioactive butyrolactone 1 could be a promising candidate in pharmaceutical field |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Antimicrobial and antioxidant activities |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Calotropis procera |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Endophytes |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ahmed Atef Elbeih , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mohamed Gamal Farahat , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Tahany Mohamed Abdelrahman , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Shimaa |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.12.18.M.Sc.2020.Ah.D | 01010110082720000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.12.18.M.Sc.2020.Ah.D | 01020110082720000 | 22.09.2023 | CD - Rom | 82720.CD |