MARC details
000 -LEADER |
fixed length control field |
03210cam a2200325 a 4500 |
003 - CONTROL NUMBER IDENTIFIER |
control field |
EG-GiCUC |
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
fixed length control field |
210208s2020 ua dh f m 000 0 eng d |
040 ## - CATALOGING SOURCE |
Original cataloging agency |
EG-GiCUC |
Language of cataloging |
eng |
Transcribing agency |
EG-GiCUC |
041 0# - LANGUAGE CODE |
Language code of text/sound track or separate title |
eng |
049 ## - LOCAL HOLDINGS (OCLC) |
Holding library |
Deposite |
097 ## - Thesis Degree |
Thesis Level |
Ph.D |
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
Classification number |
Cai01.09.12.Ph.D.2020.Ta.B |
100 0# - MAIN ENTRY--PERSONAL NAME |
Personal name |
Tasneem Mostafa Abdelmageed Soliman |
245 14 - TITLE STATEMENT |
Title |
The bone healing potential of moringa oleifera extract versus mesenchymal stem cells on glucocorticoids induced jawbone osteoporosis in albino rats : |
Remainder of title |
An animal study / |
Statement of responsibility, etc. |
Tasneem Mostafa Abdelmageed Soliman ; Supervised Zoba Hassan Ali , Dina Sabry Abdelfattah , Mohamed Ahmed Zayed |
246 15 - VARYING FORM OF TITLE |
Title proper/short title |
قدرة مستخلص المورنجا اوليفيرا مقابل الخلايا الجذعية الوسيطة على شفاء هشاشة عظم الفك المسببة بالجلوكوكورتيكويدز فى الفئران البيضاء : |
Remainder of title |
دراسة فى الحيوان |
260 ## - PUBLICATION, DISTRIBUTION, ETC. |
Place of publication, distribution, etc. |
Cairo : |
Name of publisher, distributor, etc. |
Tasneem Mostafa Abdelmageed Soliman , |
Date of publication, distribution, etc. |
2020 |
300 ## - PHYSICAL DESCRIPTION |
Extent |
185 P. : |
Other physical details |
charts , facimiles ; |
Dimensions |
25cm |
502 ## - DISSERTATION NOTE |
Dissertation note |
Thesis (Ph.D.) - Cairo University - Faculty of Oral and Dental Medicine- Department of Oral Biology |
520 ## - SUMMARY, ETC. |
Summary, etc. |
Aim: This study aimed to compare the bone healing potential of Moringa Oleifera (MO) versus Mesenchymal Stem Cells (MSCs) on glucocorticoids induced jawbone osteoporosis in Albino rats. Methodology: Thirty-six Albino rats were randomly distributed into 3 equal groups (12 per group), osteoporotic group, MSCs and MO treated groups. Four rats from each group were sacrificed after 2, 4 and 6 weeks from the treatment initiation, sacrifice times were the same for the untreated osteoporotic group. After each sacrification, the dissected jawbone was prepared for histopathological examination, histomorphometric analysis, Dual X-ray absorptiometry (DXA), Real Time Polymerase Chain Reaction (RT-PCR) and western blot. Comparisons between the 3 groups were done using ANOVA for normally distributed variables and Kruskal Wallis test for non-normally distributed variables. Results: The histopathological examination of the osteoporotic group showed progressive deterioration of bone micro-architecture, wide bone marrow cavities, few bone cells and multiple bone clefts. However, both MSCs and MO treated groups showed a gradual healing progress regarding the trabecular micro-architecture, size of marrow cavities, size, shape and abundance of osteocytes and healing of bone clefts.The histomorphometric analysis revealed that the bone area percent values decreased in the osteoporotic groups, while they increased in the MO group and increased even more in the MSCs group especially after the 3rd sacrifice (p <0.001).The DEXA analysis showed a significantly increased bone mineral density in the MSCs and MO treated groups compared to the osteoporotic groups (p <0.001) |
530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE |
Additional physical form available note |
Issued also as CD |
653 #4 - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
DXA |
653 #4 - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
Glucocorticoids |
653 #4 - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
Osteoporosis |
700 0# - ADDED ENTRY--PERSONAL NAME |
Personal name |
Dina Sabry Abdelfattah , |
Relator term |
|
700 0# - ADDED ENTRY--PERSONAL NAME |
Personal name |
Mohamed Ahmed Zayed , |
Relator term |
|
700 0# - ADDED ENTRY--PERSONAL NAME |
Personal name |
Zoba Hassan Ali , |
Relator term |
|
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) |
Cataloger |
Nazla |
Reviser |
Revisor |
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) |
Cataloger |
Shimaa |
Reviser |
Cataloger |
942 ## - ADDED ENTRY ELEMENTS (KOHA) |
Source of classification or shelving scheme |
Dewey Decimal Classification |
Koha item type |
Thesis |