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The bone healing potential of moringa oleifera extract versus mesenchymal stem cells on glucocorticoids induced jawbone osteoporosis in albino rats : (Record no. 79850)

MARC details
000 -LEADER
fixed length control field 03210cam a2200325 a 4500
003 - CONTROL NUMBER IDENTIFIER
control field EG-GiCUC
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 210208s2020 ua dh f m 000 0 eng d
040 ## - CATALOGING SOURCE
Original cataloging agency EG-GiCUC
Language of cataloging eng
Transcribing agency EG-GiCUC
041 0# - LANGUAGE CODE
Language code of text/sound track or separate title eng
049 ## - LOCAL HOLDINGS (OCLC)
Holding library Deposite
097 ## - Thesis Degree
Thesis Level Ph.D
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC)
Classification number Cai01.09.12.Ph.D.2020.Ta.B
100 0# - MAIN ENTRY--PERSONAL NAME
Personal name Tasneem Mostafa Abdelmageed Soliman
245 14 - TITLE STATEMENT
Title The bone healing potential of moringa oleifera extract versus mesenchymal stem cells on glucocorticoids induced jawbone osteoporosis in albino rats :
Remainder of title An animal study /
Statement of responsibility, etc. Tasneem Mostafa Abdelmageed Soliman ; Supervised Zoba Hassan Ali , Dina Sabry Abdelfattah , Mohamed Ahmed Zayed
246 15 - VARYING FORM OF TITLE
Title proper/short title قدرة مستخلص المورنجا اوليفيرا مقابل الخلايا الجذعية الوسيطة على شفاء هشاشة عظم الفك المسببة بالجلوكوكورتيكويدز فى الفئران البيضاء :
Remainder of title دراسة فى الحيوان
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Place of publication, distribution, etc. Cairo :
Name of publisher, distributor, etc. Tasneem Mostafa Abdelmageed Soliman ,
Date of publication, distribution, etc. 2020
300 ## - PHYSICAL DESCRIPTION
Extent 185 P. :
Other physical details charts , facimiles ;
Dimensions 25cm
502 ## - DISSERTATION NOTE
Dissertation note Thesis (Ph.D.) - Cairo University - Faculty of Oral and Dental Medicine- Department of Oral Biology
520 ## - SUMMARY, ETC.
Summary, etc. Aim: This study aimed to compare the bone healing potential of Moringa Oleifera (MO) versus Mesenchymal Stem Cells (MSCs) on glucocorticoids induced jawbone osteoporosis in Albino rats. Methodology: Thirty-six Albino rats were randomly distributed into 3 equal groups (12 per group), osteoporotic group, MSCs and MO treated groups. Four rats from each group were sacrificed after 2, 4 and 6 weeks from the treatment initiation, sacrifice times were the same for the untreated osteoporotic group. After each sacrification, the dissected jawbone was prepared for histopathological examination, histomorphometric analysis, Dual X-ray absorptiometry (DXA), Real Time Polymerase Chain Reaction (RT-PCR) and western blot. Comparisons between the 3 groups were done using ANOVA for normally distributed variables and Kruskal Wallis test for non-normally distributed variables. Results: The histopathological examination of the osteoporotic group showed progressive deterioration of bone micro-architecture, wide bone marrow cavities, few bone cells and multiple bone clefts. However, both MSCs and MO treated groups showed a gradual healing progress regarding the trabecular micro-architecture, size of marrow cavities, size, shape and abundance of osteocytes and healing of bone clefts.The histomorphometric analysis revealed that the bone area percent values decreased in the osteoporotic groups, while they increased in the MO group and increased even more in the MSCs group especially after the 3rd sacrifice (p <0.001).The DEXA analysis showed a significantly increased bone mineral density in the MSCs and MO treated groups compared to the osteoporotic groups (p <0.001)
530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE
Additional physical form available note Issued also as CD
653 #4 - INDEX TERM--UNCONTROLLED
Uncontrolled term DXA
653 #4 - INDEX TERM--UNCONTROLLED
Uncontrolled term Glucocorticoids
653 #4 - INDEX TERM--UNCONTROLLED
Uncontrolled term Osteoporosis
700 0# - ADDED ENTRY--PERSONAL NAME
Personal name Dina Sabry Abdelfattah ,
Relator term
700 0# - ADDED ENTRY--PERSONAL NAME
Personal name Mohamed Ahmed Zayed ,
Relator term
700 0# - ADDED ENTRY--PERSONAL NAME
Personal name Zoba Hassan Ali ,
Relator term
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN)
Cataloger Nazla
Reviser Revisor
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN)
Cataloger Shimaa
Reviser Cataloger
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme Dewey Decimal Classification
Koha item type Thesis
Holdings
Source of classification or shelving scheme Not for loan Home library Current library Date acquired Full call number Barcode Date last seen Koha item type Copy number
Dewey Decimal Classification   المكتبة المركزبة الجديدة - جامعة القاهرة قاعة الرسائل الجامعية - الدور الاول 11.02.2024 Cai01.09.12.Ph.D.2020.Ta.B 01010110082735000 22.09.2023 Thesis  
Dewey Decimal Classification   المكتبة المركزبة الجديدة - جامعة القاهرة مخـــزن الرســائل الجـــامعية - البدروم 11.02.2024 Cai01.09.12.Ph.D.2020.Ta.B 01020110082735000 22.09.2023 CD - Rom 82735.CD