studies on the effect of fipronil insecticide on some brain regions of male albino rats / (Record no. 80035)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 03037cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223032709.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 210228s2020 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.10.08.M.Sc.2020.Mo.S |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Mohamed Ahmed Awad Ibrahim |
| 245 10 - TITLE STATEMENT | |
| Title | studies on the effect of fipronil insecticide on some brain regions of male albino rats / |
| Statement of responsibility, etc. | Mohamed Ahmed Awad Ibrahim ; Supervised Moukhtar Hanafy Gad Moussa , Gehad Abdelfattah Hassan Elbargeesy , Zainab Sabry Othman Ahmed |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | دراسات على تأثير المبيد الحشرى فبرونيل على بعض مناطق المخ فى ذكور الجرذان البيضاء |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Mohamed Ahmed Awad Ibrahim , |
| Date of publication, distribution, etc. | 2020 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 173 P. : |
| Other physical details | charts , facimiles ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (M.Sc.) - Cairo University - Faculty of Veterinary Medicine - Department of Histology and Cytology |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Fipronil (FIP) is a widely used insecticide for many purposes in different application fields including Veterinary Medicine, agriculture and public health. The extensive usage of FIP may lead to environmental pollution and non-intentional exposure of non-target species. FIP was reported to have a neurotoxic effect against insects, and it also showed neurological hazard upon vertebrate exposure. However, slight is known about its potential neurotoxic effects and its molecular mechanisms on the non-target organisms. Therefore, this study aimed to assess apoptosis, oxidative stress, genotoxicity, neuroinflammation and histopathological alterations in discrete brain regions; cerebral cortex , hippocampus, caudate and putamen, cerebellum, brain stem and diencephalon after sub-acute exposure of rats to FIP.Twenty adult male albino rats were divided into 2 groups (10 rats/ group), control group and FIP treated group. Each rat of the treated group received a daily dose of FIP (technical grade) at 10 mg/kg body weight by oral gavage for 45 days.The discrete brain regions were processed to examine oxidative stress induced macromolecular modifications. Besides, Tumor necrosis factor-Ü (TNF- Ü )and B - cell lymphoma 2 (Bcl-2) gene expression and immunoreactivity for caspase-3 (active form), inducible nitric oxide synthase(iNOS) and glial fibrillary acidic protein (GFAP) were evaluated. In addition, histopathological assessment was performed. Our results revealed that FIP significantly raised malondialdehyde (MDA), protein carbonyls and DNA fragmentation (p{u2264}0.05) |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Apoptosis |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Fiproni |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Oxidative stress |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Gehad Abdelfattah Hassan Elbargeesy , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Moukhtar Hanafy Gad Moussa , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Zainab Sabry Othman Ahmed , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Shimaa |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.10.08.M.Sc.2020.Mo.S | 01010110082822000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.10.08.M.Sc.2020.Mo.S | 01020110082822000 | 22.09.2023 | CD - Rom | 82822.CD |