T central memory cells in early versus late cases of localized and generalized non segmental vitiligo / (Record no. 80472)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 03063cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223032722.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 210401s2020 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.11.10.M.Sc.2020.Na.T |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Nada Nasser Abdelaziz |
| 245 10 - TITLE STATEMENT | |
| Title | T central memory cells in early versus late cases of localized and generalized non segmental vitiligo / |
| Statement of responsibility, etc. | Nada Nasser Abdelaziz ; Supervised Salonas Ali Marzouk , Iman Sany Zaky , Nouran Nabil Momen |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | خلايا الذاكرة المركزية التائية فى حالات البهاق غير القطاعى المحدودة والمنتشرة، المبكرة والمتأخرة |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Nada Nasser Abdelaziz , |
| Date of publication, distribution, etc. | 2020 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 102 P . : |
| Other physical details | charts , facsmilies ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Dermatology and Venerology |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Background: Circulating TCM are able to migrate back and forth through the blood and lymph to tissues such as the skin. Antigen-specific TCM have been identified in the blood of vitiligo patients. TCM sense antigen, secrete cytokines, chemokines and cooperate with TRM to maintain disease. Inhibiting TCM cells recruitment to the skin with FTY720 or depleting TCM with low-dose Thy1.1 antibody reversed the disease. Aim of work: The current study aimed to characterize the role of central memory T cell in pathogenesis of the disease and its diversity in blood of early versus late cases of generalized and localized non segmental vitiligo and to compare them to controls using multiparametric flow cytometry. Patients and methods: This study included 61 patients of non segmental vitiligo and 30 healthy controls. Detailed history was taken from each patient ,VASI, VES, and VIDA scores were assessed in every patient. Blood samples were taken , processed and stained for CD8,CD3, CCR7,CD45RO in all cases and controls.Level of TCM cells was measured in blood of all cases and controls using multiparametric flow cytometry. Results: Level of TCM was statistically higher (P value < 0.001) in controls than in cases , Early group of patients showed significantly higher TCM level (P value=0.032) than late group . No significant difference was found in level of TCM among localized versus generalized groups, patients with different VIDA scores (stable group and active group of vitiligo) . Also no correlation was found between level of TCM in patients with different VASI scores ,VES scores and different number of lesions |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Generalized non segmental vitiligo |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Localized |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | T central memory cells |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Iman Sany Zaky , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Nouran Nabil Momen , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Salonas Ali Marzouk , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Amira |
| Reviser | Cataloger |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.11.10.M.Sc.2020.Na.T | 01010110083133000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.11.10.M.Sc.2020.Na.T | 01020110083133000 | 22.09.2023 | CD - Rom | 83133.CD |