Assessment of serum activina level and its value as a biomarker for predicting subsequent asthma in wheezy infants / (Record no. 80577)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 03024cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223032726.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 210410s2021 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | Ph.D |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.11.28.Ph.D.2021.He.A |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Heba Ahmed Said Mahmoud Raslan |
| 245 10 - TITLE STATEMENT | |
| Title | Assessment of serum activina level and its value as a biomarker for predicting subsequent asthma in wheezy infants / |
| Statement of responsibility, etc. | Heba Ahmed Said Mahmoud Raslan ; Supervised Mona Mustafa Elfalaki , Mohammed Abdelfattah Abdelmotey , Nihal Mohamed Elrifai |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | فى المصل كعلامة بيولوجية للتنبؤ بالربو اللاحق فى الرضع والأطفال الصغار المصابين بأزيز صدرى متكرر A تقييم مستوى أكتيفين |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Heba Ahmed Said Mahmoud Raslan , |
| Date of publication, distribution, etc. | 2021 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 203 P. : |
| Other physical details | charts , facsimiles ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (Ph.D.) - Cairo University - Faculty of Medicine- Department of Pediatrics |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Background: Activin A cytokine has grabbed attention regarding its role in inflammation and airway remodeling in asthma as it regulates airway inflammatory cells and airway remodeling. However, knowledge regarding its role in wheezy infants is limited. Patients and Methods: The present study was designed as a case control study that included two groups. First group, 40 Egyptian infants less than 2 years referred to the allergy clinic with history of their first or second attack of wheezing with mean age 14.925 ± 5.942 months with male to female ratio of 1.35, and second group, their matched control group (n=40). After comprehensive clinical assessment, blood samples were taken from the patients in order to assess serum activin-A, IgE and CBC measurements. Results: Patients had statistically significant higher activin A level compared to healthy controls (529.8 ± 358.4 vs 227.9 ± 63.4 pg/ml, p<0.001). Activin-A levels had a strong positive correlation with IgE levels (r=0.760) (p<0.001) and eosinophilic count (r=0.758) (p<0.001). Predictive ability of activin-A in discriminating wheezy infants from healthy controls showed that activin-A had high specificity of 95% and low sensitivity (55%). Mean serum activin A was significantly higher in patients who had history of recurrence of wheeze and hospital admission at follow-up. There were significant direct correlations between serum activin A and recurrence of wheezes, number of attacks and hospital admission within 6 months of the study at follow-up |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Activin A |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Asthma |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Children |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mohammed Abdelfattah Abdelmotey , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mona Mustafa Elfalaki , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Nihal Mohamed Elrifai , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Shimaa |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.11.28.Ph.D.2021.He.A | 01010110083191000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.11.28.Ph.D.2021.He.A | 01020110083191000 | 22.09.2023 | CD - Rom | 83191.CD |