Nano-systems for enhancing delivery of a certain anti-inflammatory drug / (Record no. 80656)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02417cam a2200313 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 210415s2021 ua d f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.08.08.M.Sc.2021.Sa.N |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Sadek Ahmed Sadek |
| 245 10 - TITLE STATEMENT | |
| Title | Nano-systems for enhancing delivery of a certain anti-inflammatory drug / |
| Statement of responsibility, etc. | Sadek Ahmed Sadek ; Supervised Mohamed Aly Kassem , Sinar Sayed Fouad |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | أنظمة نانوية لتحسين توصيل عقار معين مضاد للالتهابات |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Sadek Ahmed Sadek , |
| Date of publication, distribution, etc. | 2021 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 109 P . : |
| Other physical details | charts ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Pharmaceutics |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Transdermal delivery of drug through the skin provides a successful method for the treatment of rheumatoid arthritis (RA). However, stratum corneum (SC) presents the main barrier for transdermal delivery. In order to overcome this barrier many strategies have been adopted. Nanocarriers used to improve dermal and transdermal delivery are colloids including liposomes, ethosomes, transferosomes and bilosomes.Lornoxicam (LX) is an oxicam derivative. It{u2019}s an anti-inflammatory, antipyretic and analgesic drug prescribed for indications like rheumatoid arthritis. It acts by inhibiting phospholipase A2 resulting in the inhibition of arachidonic acid synthesis and controlling prostaglandins and leukotriene synthesis eventually, leading to anti-inflammatory, immunosuppressive and the anti-proliferative effect. It is practically insoluble in water; it needs frequent oral administration due to its short half- life (3-4 h). Moreover, parenteral administration isn{u2019}t recommended against chronic condition. Accordingly, our study aims to develop LX as controlled release nanocarriers transdermal gels in order to improve drug delivery across the skin and to evaluate in vivo analgesic and anti-inflammatory activity with decreased GIT, renal and hematological adverse effects |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Anti-inflammatory drug |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Enhancing delivery |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Nano-systems |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mohamed Aly Kassem , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Sinar Sayed Fouad , |
| Relator term | |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Amira |
| Reviser | Cataloger |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.08.08.M.Sc.2021.Sa.N | 01010110083267000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.08.08.M.Sc.2021.Sa.N | 01020110083267000 | 22.09.2023 | CD - Rom | 83267.CD |