MARC details
000 -LEADER |
fixed length control field |
02977cam a2200325 a 4500 |
003 - CONTROL NUMBER IDENTIFIER |
control field |
EG-GiCUC |
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
fixed length control field |
210428s2021 ua dh f m 000 0 eng d |
040 ## - CATALOGING SOURCE |
Original cataloging agency |
EG-GiCUC |
Language of cataloging |
eng |
Transcribing agency |
EG-GiCUC |
041 0# - LANGUAGE CODE |
Language code of text/sound track or separate title |
eng |
049 ## - LOCAL HOLDINGS (OCLC) |
Holding library |
Deposite |
097 ## - Thesis Degree |
Thesis Level |
M.Sc |
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
Classification number |
Cai01.24.05.M.Sc.2021.Ha.S |
100 0# - MAIN ENTRY--PERSONAL NAME |
Personal name |
Hala Mohamed Salah Eldin Hassen |
245 10 - TITLE STATEMENT |
Title |
Spectroscopic properties of carbon nanomaterials and their biological applications : |
Remainder of title |
In vitro study / |
Statement of responsibility, etc. |
Hala Mohamed Salah Eldin Hassen ; Supervised Tarek A. Etayeb , Abdallah F. Zedan , Mona B. Mohamed |
246 15 - VARYING FORM OF TITLE |
Title proper/short title |
دراسة معمليه : |
Remainder of title |
الخواص الطيفية للمواد الكربونية النانونية و تطبيقاتها البيولوجية |
260 ## - PUBLICATION, DISTRIBUTION, ETC. |
Place of publication, distribution, etc. |
Cairo : |
Name of publisher, distributor, etc. |
Hala Mohamed Salah Eldin Hassen , |
Date of publication, distribution, etc. |
2021 |
300 ## - PHYSICAL DESCRIPTION |
Extent |
85 P . : |
Other physical details |
charts , facsmilies ; |
Dimensions |
25cm |
502 ## - DISSERTATION NOTE |
Dissertation note |
Thesis (M.Sc.) - Cairo University - National Institute of Laser Enhanced Science - Department of Laser Applications in Metrology, Photochemistry and Agriculture |
520 ## - SUMMARY, ETC. |
Summary, etc. |
The flurescent carbin dots (CDs) have attracted great interest in the recent years in different fields such as bioimaging. The CDs fluorescent probes offer several advantages such as chemical stability, tunable optical properties, relatively low cost, simple preparation in addition to the great biocompatibility. In this thesis, fluorescent carbon dots were prepared adopting microwave-assisted solvothermal method using citric acid (CA) and ethylenediamine (EDA) as molecular precursors. The surface of the microwave-synthesized CDs was modified using two different passivation methods in order to tune their optical properties. The CDs were passivated by surface modification with polyethylene glycol (PEGylation) and by silica (SiO₂) coating. The prepared different CDs were characterized by TEM, XRD, FTIR, UV-Vis absorption and emission spectroscopy. The spectroscopic studies revealed the enhancement effect of the surface modification on the fluorescence intensity and quantum yield of the prepared carbon dot. The surface modification with PEG resulted in superior improvement to the emission properties of the CDs with a 16% increase of the fluorescence intensity compared to as prepared CDs. In order to investigate the biocompatibility of nanoparticles, sulphorhodamine-B (SRB) assay using HepG2 cell line was performed which indicate no toxic effect of CD and PEGylated CDs up to concentration 125 mg/ml after that cell viability decrease with increasing concentration while the SiO₂-CDs didn{u2019}t show any toxic effect even at very high concentration 500 og/ml |
530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE |
Additional physical form available note |
Issued also as CD |
653 #4 - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
Carbon nanomaterials |
653 #4 - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
EDA |
653 #4 - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
Spectroscopic properties |
700 0# - ADDED ENTRY--PERSONAL NAME |
Personal name |
Abdallah F. Zedan , |
Relator term |
|
700 0# - ADDED ENTRY--PERSONAL NAME |
Personal name |
Mona B. Mohamed , |
Relator term |
|
700 0# - ADDED ENTRY--PERSONAL NAME |
Personal name |
Tarek A. Etayeb , |
Relator term |
|
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) |
Cataloger |
Amira |
Reviser |
Cataloger |
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) |
Cataloger |
Nazla |
Reviser |
Revisor |
942 ## - ADDED ENTRY ELEMENTS (KOHA) |
Source of classification or shelving scheme |
Dewey Decimal Classification |
Koha item type |
Thesis |