Localization of indicators for epithelial mesenchymal transformation in gingiva from chronic periodontitis patients as compared to healthy individuals : (Record no. 80810)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 03684cam a2200337 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223032733.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 210505s2021 ua dh f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.09.12.M.Sc.2021.Ka.L |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Karim Wasfi Wadiea Yacoup |
| 245 10 - TITLE STATEMENT | |
| Title | Localization of indicators for epithelial mesenchymal transformation in gingiva from chronic periodontitis patients as compared to healthy individuals : |
| Remainder of title | Case control study / |
| Statement of responsibility, etc. | Karim Wasfi Wadiea Yacoup ; Supervised Marwa Magdy Saad Abbass , Maha Hasan Bashir |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | دراسة للحالات و الشواهد : |
| Remainder of title | تحديد مؤشرات تحول النسيج الطلائى للنسيج اللحائى فى لثه مرضى التهاب اللثه المزمه مقارنه بلثه الأصحاء غير المصابين بالمرض |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Karim Wasfi Wadiea Yacoup , |
| Date of publication, distribution, etc. | 2021 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 109 P . : |
| Other physical details | charts , facsmilies ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (M.Sc.) - Cairo University - Faculty of Oral and Dental Medicine - Department of Oral Biology |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Epithelial- mesenchymal transition (EMT) is a process by which epithelial cells acquire a mesenchymal- like phenotype. This may be induced by exposure to gram- negative bacteria. However, it has been proposed that EMT is responsible for the pathogenesis of several diseases, the relationship between EMT process and the severity of periodontitis has not previously been investigated. Therefore, the aim of this study was to investigate the possibility of the presence of EMT indicators (TGF- Ý1, Vimenten, E-Cadherin) in the gingival tissue samples taken from periodontally diseased individuals as compared to tissue samples taken from individuals with healthy gingival tissues. Methods: Total of 36 participants have been recruited in this study. The participants were divided according to their periodontal status into two main groups (healthy and periodntitis groups). The periodontitis group was further subclassified into mild, moderate and severe periodontitis subgroups, 9 patients in each group. Gingival tissue samples have been harvested during periodontal surgery and extraction of the periodontally hopeless teeth for the periodontitis patients. Healthy gingival tissues have been taken during the premolar extraction (Orthodontic ttt) or third molar extraction for the healthy controls .The dissected gingival samples were processed to be embedded in paraffin wax. Sections of five microns were cut and mounted on glass slides then deparaffinized, rehydrated in descending grades of alcohol and subjected to histological staining by hematoxylin eosin and histomorphometric analysis by digital image analysis. Samples were also subjected to quantitative real-time polymerase chain reaction for transforming growth factor-Ý1, Vimenten and E-Cadherin. Results: The H & E stained sections from the normal gingival group showed normal epithelium and connective tissue appearance with no clear signs of inflammation. The H & E stained sections from mild periodontitis subgroup showed similar appearance to that of the healthy group with slight increase in the epithelial thickness and inflammatory cells count |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Chronic periodontitis patients |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Epithelial- mesenchymal transition (EMT) |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Gingiva |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Maha Hasan Bashir , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Marwa Magdy Saad Abbass , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Amira |
| Reviser | Cataloger |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.09.12.M.Sc.2021.Ka.L | 01010110083367000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.09.12.M.Sc.2021.Ka.L | 01020110083367000 | 22.09.2023 | CD - Rom | 83367.CD |