Impact of infectious episodes in induction phase chemotherapy on the morbidity and mortality of pediatric patients with burkitt{u2019}s lymphoma / (Record no. 80847)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 03301cam a2200349 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | EG-GiCUC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250223032734.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 210509s2021 ua d f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EG-GiCUC |
| Language of cataloging | eng |
| Transcribing agency | EG-GiCUC |
| 041 0# - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Deposite |
| 097 ## - Thesis Degree | |
| Thesis Level | M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| Classification number | Cai01.19.05.M.Sc.2021.Di.I |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Dina Basil Elsabbagh |
| 245 10 - TITLE STATEMENT | |
| Title | Impact of infectious episodes in induction phase chemotherapy on the morbidity and mortality of pediatric patients with burkitt{u2019}s lymphoma / |
| Statement of responsibility, etc. | Dina Basil Elsabbagh ; Supervised Lobna Shalaby , Hisham Fahmi , Marwa Mohamed Fathy Elswify |
| 246 15 - VARYING FORM OF TITLE | |
| Title proper/short title | تأثير النوبات المعدية فى مرحلة العلاج الكيميائى التحفيزى على مرضية ووفيات مرضى الأطفال المصابين بسرطان الغدد اللمفاوية بوركيت |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Cairo : |
| Name of publisher, distributor, etc. | Dina Basil Elsabbagh , |
| Date of publication, distribution, etc. | 2021 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 150 P. : |
| Other physical details | charts ; |
| Dimensions | 25cm |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Thesis (M.Sc.) - Cairo University - National Cancer Institute - Department of Pediatric Oncology |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Background/objective; The outcome of childhood Burkitt{u2019}s lymphoma (BL) has improved steadily over the past decades with intensive chemotherapy regimens but chemotherapy-Induced neutropenia (CIN) remains the most serious and the major dose-limiting toxicity of systemic chemotherapy. This study objective was to assess the morbidities and mortalities of infectious episodes during induction phase chemotherapy. Methods: A retrospective study including all patients 18 years old or younger diagnosed with BL and treated according to the modified LMB 96 protocol at the National Cancer Institute, Cairo university from January 2016 to December 2019 and their follow up till June 2020. Results:There were303 infectious episodes in 152 patients.Typhlitis/colitis was the commonest clinically documented infection (54.4%), followed by mucositis (40.5%), and chest infection/pneumonia (38.2%). In the microbiologically documented episodes, Gram negative organisms represented 57%. The main cause of death was likely sepsis (65.4%). Mortality was higher in group C patients (18.8%) compared to group B patients (7.8%). There were no mortalities in group A patients (P value = 0.011). Mortality of microbiologically documented episodes represented 78.8% (P value <0.001), including those of multidrug resistant Gram negative bacteremia representing 37.2 % (P value <0.001). Among predictors of outcome, thrombocytopenia, anemia, impaired electrolytes, and impaired liver and renal function tests, were associated with higher mortality rate (37.3%, 20.2%, 25.2%, 37.5%, and 72.7% respectively) (P value <0.001). Additionally, poor general condition before starting chemotherapy, presence of active disease, and earlier onset of fever and neutropenia were associated with poorer outcome (P value <0.001) |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Burkitt{u2019}slymphoma |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Children |
| 653 #4 - INDEX TERM--UNCONTROLLED | |
| Uncontrolled term | Febrile neutropenia |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Hisham Fahmi , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Lobna Shalaby , |
| Relator term | |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Marwa Mohamed Fathy Elswify , |
| Relator term | |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Nazla |
| Reviser | Revisor |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
| Cataloger | Shimaa |
| Reviser | Cataloger |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Thesis |
| Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.19.05.M.Sc.2021.Di.I | 01010110083395000 | 22.09.2023 | Thesis | ||
| Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.19.05.M.Sc.2021.Di.I | 01020110083395000 | 22.09.2023 | CD - Rom | 83395.CD |