MARC details
| 000 -LEADER |
|---|
| fixed length control field |
02867cam a2200325 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER |
|---|
| control field |
EG-GiCUC |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
|---|
| fixed length control field |
210520s2020 ua dho f m 000 0 eng d |
| 040 ## - CATALOGING SOURCE |
|---|
| Original cataloging agency |
EG-GiCUC |
| Language of cataloging |
eng |
| Transcribing agency |
EG-GiCUC |
| 041 0# - LANGUAGE CODE |
|---|
| Language code of text/sound track or separate title |
eng |
| 049 ## - LOCAL HOLDINGS (OCLC) |
|---|
| Holding library |
Deposite |
| 097 ## - Thesis Degree |
|---|
| Thesis Level |
Ph.D |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
|---|
| Classification number |
Cai01.19.04.Ph.D.2020.Em.A |
| 100 0# - MAIN ENTRY--PERSONAL NAME |
|---|
| Personal name |
Eman Sobhy Elbanna |
| 245 10 - TITLE STATEMENT |
|---|
| Title |
Adjuvant short XELOX followed by capecitabine for stage III colon cancer : |
| Remainder of title |
Phase II study / |
| Statement of responsibility, etc. |
Eman Sobhy Elbanna ; Supervised Mostafa Mahmoud Elserafi , Ghada Mahmoud Sherif , Yahia Mahmoud Ismail |
| 246 15 - VARYING FORM OF TITLE |
|---|
| Title proper/short title |
دراسه تجريبية لإعطاء علاج الزيلوكس لمدة قصيره يليه عقار الكابسيتابين كعلاج مصاحب في حالات المرحلة الثالثة من سرطان القولون |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
|---|
| Place of publication, distribution, etc. |
Cairo : |
| Name of publisher, distributor, etc. |
Eman Sobhy Elbanna , |
| Date of publication, distribution, etc. |
2020 |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Extent |
160 P . : |
| Other physical details |
charts , facsmilies , photographs ; |
| Dimensions |
25cm |
| 502 ## - DISSERTATION NOTE |
|---|
| Dissertation note |
Thesis (Ph.D.) - Cairo University - National Cancer Institute - Department of Oncology (Medical) |
| 520 ## - SUMMARY, ETC. |
|---|
| Summary, etc. |
Background: The standard of care for adjuvant chemotherapy for stage III colon cancer is six months of oxaliplatincontaining regimen. Despite its survival benefits; still the cumulative neurotoxicity is a deleterious challenging problem. Aim: Evaluation of the efficacy and toxicity of shorter duration of Oxaliplatin in the adjuvant treatment for stage III colon cancer. Patients & Methods: A prospective single arm phase II study included a total number of 50 patients with resected stage III colon cancer presented to NCI and Tanta cancer center. Patients received adjuvant 3-months of XELOX (Capecitabine and Oxaliplatin) followed by 3 months of single agent Capecitabine. Results: The median age of patients was 43years (range: 21- 70) with male predominance. The majority of patients (70%) had right-sided lesions and N1 stage (64%). After a median follow up period of 36.8 months (range: 9.5-50.8); the 3-year cumulative disease free survival (DFS) & overall survival (OS) were 57.2 &86.3% respectively. Patients{u2019} age, presence of comorbidity, higher grade, development of chemotherapy-related peripheral neuropathy (PN), N2 stage , perineural invasion (PNI) and lymph node ratio (LNR) > 0.25 were significantly associated with worse DFS whereas, the latter two were significantly related to worse OS . Diarrhea, vomiting, hand-foot syndrome and PN were the most common grade 3 toxicity. The latter was significantly higher in patients with preexisting diabetes |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE |
|---|
| Additional physical form available note |
Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
Adjuvant |
| 653 #4 - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
Colon cancer |
| 653 #4 - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
Stage III |
| 700 0# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Ghada Mahmoud Sherif , |
| Relator term |
|
| 700 0# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Mostafa Mahmoud Elserafi , |
| Relator term |
|
| 700 0# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Yahia Mahmoud Ismail , |
| Relator term |
|
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) |
|---|
| Cataloger |
Amira |
| Reviser |
Cataloger |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) |
|---|
| Cataloger |
Nazla |
| Reviser |
Revisor |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| Source of classification or shelving scheme |
Dewey Decimal Classification |
| Koha item type |
Thesis |
