MARC details
| 000 -LEADER |
|---|
| fixed length control field |
031990000a22003370004500 |
| 003 - CONTROL NUMBER IDENTIFIER |
|---|
| control field |
EG-GICUC |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
|---|
| fixed length control field |
091106s2003 ua a f m 000 00eng d |
| 040 ## - CATALOGING SOURCE |
|---|
| Original cataloging agency |
EG-GICUC |
| Language of cataloging |
eng |
| Transcribing agency |
EG-GICUC |
| 041 0# - LANGUAGE CODE |
|---|
| Language code of text/sound track or separate title |
Eng |
| 049 ## - LOCAL HOLDINGS (OCLC) |
|---|
| Holding library |
Deposite |
| 097 ## - Thesis Degree |
|---|
| Thesis Level |
M.Sc |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
|---|
| Classification number |
Cai01.12.21.M.Sc.2003.Gh.I. |
| 100 0# - MAIN ENTRY--PERSONAL NAME |
|---|
| Personal name |
Ghada Abd El monem Zhran |
| 245 10 - TITLE STATEMENT |
|---|
| Title |
Immunological and Histological Effects of Nigella Sativa on lead exposure in mice / |
| Statement of responsibility, etc. |
Ghada Abd El monem Zhran ; supervised Salwa Fouad , Azza ElAmir , Isaad ElDarwish |
| 246 15 - VARYING FORM OF TITLE |
|---|
| Title proper/short title |
التاثيرات المناعية والهيستولوجية لنبات حبة البركة على الفئران المعرضة للرصاص |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
|---|
| Place of publication, distribution, etc. |
Cairo : |
| Name of publisher, distributor, etc. |
Ghada Abd El monem Zhran , |
| Date of publication, distribution, etc. |
2003 |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Extent |
84L : |
| Other physical details |
ill ; |
| Dimensions |
30cm |
| 502 ## - DISSERTATION NOTE |
|---|
| Dissertation note |
Thesis (M.Sc.) - Cairo University - Faculty Of Science - Department Of Zoology |
| 520 ## - SUMMARY, ETC. |
|---|
| Summary, etc. |
It has become apparent that heavy metals can alter the humoral and cell - mediated immune responses and , in effect , play a role in the development of immunopathologic disordersInhalation of metal dusts and fumes can induce a wide range of lung pathology , including airways disorders , cancer , and parenchymal diseasesIn the present study , the modulation of an immunosuppressive state induced by lead (Pb) was one of our special interestTo accurately determine this relationship , a quantitative and qualitative study are requiredThe a bility of Pb to alter the humoral and cell mediated immune responses as well as to develop lesions in various organs were previously demonstratedAdministration of 100æg / day of Pb (gp A) into male Albino mice for two weeks induced a significant increase (P< 0001) in the lead serum concentrations compared to normal mice (gp C) After treatment with 12 g / day of Nigella sativa (NS) after being exposed to Pb for 1 week , a significant decrease (P<0001) was observed in Pb serum level as compared to gp AMice administered with Pb demonstrated a significant decrease in the number of circulating lymphocytes as compared to normal mice (P<0001) , a finding which was associated with a generalized depletion of thymocytes , and an increase in neutrophil countsAdministration of NS for 1wk recovered the lymphocyte count to normal , and partially recuperated thymus to its normal appearanceThe level of serum IFN - was increased in mice exposed to Pb (gp A) alone or together with NS (gp D and F) ; this increase level was maximal when NS was given before or after Pb intakeHowever , administration of NS alone (gp E) had no effect on the level of IFN - s compared to that of control group (gp C) TNF - was significantly decreased (P< 005) in mice exposed to Pb (gp A) or to NS (gp E) Together these data demonstrate that NS can exert an immune enhancer role in modulating the response against lead detoxification processes |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE |
|---|
| Additional physical form available note |
Issued also as CD |
| 653 #4 - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
Histological |
| 653 #4 - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
Immunological |
| 653 #4 - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
Mice |
| 653 #4 - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
Nigella sativa |
| 700 0# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Azza ElAmir , |
| Relator term |
|
| 700 0# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Isaad ElDarwish , |
| Relator term |
|
| 700 0# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Salwa Fouad , |
| Relator term |
|
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) |
|---|
| Cataloger |
Enas |
| Reviser |
Cataloger |
| 905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) |
|---|
| Cataloger |
Mustafa |
| Reviser |
Revisor |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| Source of classification or shelving scheme |
Dewey Decimal Classification |
| Koha item type |
Thesis |
