Advanced Pharmacological Studies on the Progesterone Hormone in Mares and Cows / (Record no. 81151)
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000 -LEADER | |
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fixed length control field | 02954cam a2200349 a 4500 |
003 - CONTROL NUMBER IDENTIFIER | |
control field | EG-GiCUC |
005 - DATE AND TIME OF LATEST TRANSACTION | |
control field | 20250223032744.0 |
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
fixed length control field | 210603s2021 ua d f m 000 0 eng d |
040 ## - CATALOGING SOURCE | |
Original cataloging agency | EG-GiCUC |
Language of cataloging | eng |
Transcribing agency | EG-GiCUC |
041 0# - LANGUAGE CODE | |
Language code of text/sound track or separate title | eng |
049 ## - LOCAL HOLDINGS (OCLC) | |
Holding library | Deposite |
097 ## - Thesis Degree | |
Thesis Level | Ph.D |
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
Classification number | Cai01.10.15.Ph.D.2021.Ah.A |
100 0# - MAIN ENTRY--PERSONAL NAME | |
Personal name | Ahmed Nagy Mohamed |
245 10 - TITLE STATEMENT | |
Title | Advanced Pharmacological Studies on the Progesterone Hormone in Mares and Cows / |
Statement of responsibility, etc. | Ahmed Nagy Mohamed ; Supervised Attia H. Atta , Abdelmohsen M. Hammam , Walter H. Hsu |
246 15 - VARYING FORM OF TITLE | |
Title proper/short title | دراسات فارماكولوجية متقدمة على هرمون البروجستيرون فى الافراس و الابقار |
260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
Place of publication, distribution, etc. | Cairo : |
Name of publisher, distributor, etc. | Ahmed Nagy Mohamed , |
Date of publication, distribution, etc. | 2021 |
300 ## - PHYSICAL DESCRIPTION | |
Extent | 150 P . : |
Other physical details | charts ; |
Dimensions | 25cm |
502 ## - DISSERTATION NOTE | |
Dissertation note | Thesis (Ph.D.) - Cairo University - Faculty of Veterinary Medicine - Department of Vet. Pharmacology |
520 ## - SUMMARY, ETC. | |
Summary, etc. | The present study aimed to investigate the mRNA and protein expressions of nuclear progesterone (P4) receptors; PRA and PRB in mares and cows during the estrous cycle, pregnancy and parturition. RT-qPCR was used to quantify the mRNA expression for PRA and PRB and the difference between mRNA expressions for both genes was compared using the xxCt method. While the Western blot technique was used to compare the protein expression, the band intensity was analyzed using Image J. The tissue P4 concentration was measured using the enzyme immunoassay (EIA). The mRNA and protein expressions for PRA were significantly higher (P<0.0001) in equine placental tissue compared to the PRB mRNA and protein expressions. The expression of PRA mRNA in the cyclic mares was higher (P<0.005) during estrus than diestrus, however, there was no difference in the expression of PRB in the two phases. On the other hand, the protein expression for both PRA and PRB was higher (P<0.005) in estrus compared to the diestrus. The endometrial P4 concentration during diestrus was lower (P<0.005) than in estrus. Both PRA and PRB mRNA (P<0.005) and protein expression (P<0.0005) in cows' myometrial tissues decreased at term compared to the pregnancy. Also, the concentration of P4 in myometrial tissue decreased (P<0.005) in cows at parturition. The expression of mRNA for both isoforms PRA and PRB was high in the early luteal phase (ELP) (P<0.05) compared to the middle and late luteal phases (MLP and LLP). The protein expression of PRB was higher (P<0.05) in ELP compared to MLP and LLP. On the other hand, the protein expression of PRA did not change between all the phases |
530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
Additional physical form available note | Issued also as CD |
653 #4 - INDEX TERM--UNCONTROLLED | |
Uncontrolled term | Cows |
653 #4 - INDEX TERM--UNCONTROLLED | |
Uncontrolled term | Progesterone |
653 #4 - INDEX TERM--UNCONTROLLED | |
Uncontrolled term | Receptors |
700 0# - ADDED ENTRY--PERSONAL NAME | |
Personal name | Abdelmohsen M. Hammam , |
Relator term | |
700 0# - ADDED ENTRY--PERSONAL NAME | |
Personal name | Attia H. Atta , |
Relator term | |
700 0# - ADDED ENTRY--PERSONAL NAME | |
Personal name | Walter H. Hsu , |
Relator term | |
856 ## - ELECTRONIC LOCATION AND ACCESS | |
Uniform Resource Identifier | <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a> |
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
Cataloger | Amira |
Reviser | Cataloger |
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN) | |
Cataloger | Nazla |
Reviser | Revisor |
942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
Source of classification or shelving scheme | Dewey Decimal Classification |
Koha item type | Thesis |
Source of classification or shelving scheme | Not for loan | Home library | Current library | Date acquired | Full call number | Barcode | Date last seen | Koha item type | Copy number |
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Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | قاعة الرسائل الجامعية - الدور الاول | 11.02.2024 | Cai01.10.15.Ph.D.2021.Ah.A | 01010110083574000 | 22.09.2023 | Thesis | ||
Dewey Decimal Classification | المكتبة المركزبة الجديدة - جامعة القاهرة | مخـــزن الرســائل الجـــامعية - البدروم | 11.02.2024 | Cai01.10.15.Ph.D.2021.Ah.A | 01020110083574000 | 22.09.2023 | CD - Rom | 83574.CD |