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Advanced Pharmacological Studies on the Progesterone Hormone in Mares and Cows / (Record no. 81151)

MARC details
000 -LEADER
fixed length control field 02954cam a2200349 a 4500
003 - CONTROL NUMBER IDENTIFIER
control field EG-GiCUC
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20250223032744.0
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 210603s2021 ua d f m 000 0 eng d
040 ## - CATALOGING SOURCE
Original cataloging agency EG-GiCUC
Language of cataloging eng
Transcribing agency EG-GiCUC
041 0# - LANGUAGE CODE
Language code of text/sound track or separate title eng
049 ## - LOCAL HOLDINGS (OCLC)
Holding library Deposite
097 ## - Thesis Degree
Thesis Level Ph.D
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC)
Classification number Cai01.10.15.Ph.D.2021.Ah.A
100 0# - MAIN ENTRY--PERSONAL NAME
Personal name Ahmed Nagy Mohamed
245 10 - TITLE STATEMENT
Title Advanced Pharmacological Studies on the Progesterone Hormone in Mares and Cows /
Statement of responsibility, etc. Ahmed Nagy Mohamed ; Supervised Attia H. Atta , Abdelmohsen M. Hammam , Walter H. Hsu
246 15 - VARYING FORM OF TITLE
Title proper/short title دراسات فارماكولوجية متقدمة على هرمون البروجستيرون فى الافراس و الابقار
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Place of publication, distribution, etc. Cairo :
Name of publisher, distributor, etc. Ahmed Nagy Mohamed ,
Date of publication, distribution, etc. 2021
300 ## - PHYSICAL DESCRIPTION
Extent 150 P . :
Other physical details charts ;
Dimensions 25cm
502 ## - DISSERTATION NOTE
Dissertation note Thesis (Ph.D.) - Cairo University - Faculty of Veterinary Medicine - Department of Vet. Pharmacology
520 ## - SUMMARY, ETC.
Summary, etc. The present study aimed to investigate the mRNA and protein expressions of nuclear progesterone (P4) receptors; PRA and PRB in mares and cows during the estrous cycle, pregnancy and parturition. RT-qPCR was used to quantify the mRNA expression for PRA and PRB and the difference between mRNA expressions for both genes was compared using the xxCt method. While the Western blot technique was used to compare the protein expression, the band intensity was analyzed using Image J. The tissue P4 concentration was measured using the enzyme immunoassay (EIA). The mRNA and protein expressions for PRA were significantly higher (P<0.0001) in equine placental tissue compared to the PRB mRNA and protein expressions. The expression of PRA mRNA in the cyclic mares was higher (P<0.005) during estrus than diestrus, however, there was no difference in the expression of PRB in the two phases. On the other hand, the protein expression for both PRA and PRB was higher (P<0.005) in estrus compared to the diestrus. The endometrial P4 concentration during diestrus was lower (P<0.005) than in estrus. Both PRA and PRB mRNA (P<0.005) and protein expression (P<0.0005) in cows' myometrial tissues decreased at term compared to the pregnancy. Also, the concentration of P4 in myometrial tissue decreased (P<0.005) in cows at parturition. The expression of mRNA for both isoforms PRA and PRB was high in the early luteal phase (ELP) (P<0.05) compared to the middle and late luteal phases (MLP and LLP). The protein expression of PRB was higher (P<0.05) in ELP compared to MLP and LLP. On the other hand, the protein expression of PRA did not change between all the phases
530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE
Additional physical form available note Issued also as CD
653 #4 - INDEX TERM--UNCONTROLLED
Uncontrolled term Cows
653 #4 - INDEX TERM--UNCONTROLLED
Uncontrolled term Progesterone
653 #4 - INDEX TERM--UNCONTROLLED
Uncontrolled term Receptors
700 0# - ADDED ENTRY--PERSONAL NAME
Personal name Abdelmohsen M. Hammam ,
Relator term
700 0# - ADDED ENTRY--PERSONAL NAME
Personal name Attia H. Atta ,
Relator term
700 0# - ADDED ENTRY--PERSONAL NAME
Personal name Walter H. Hsu ,
Relator term
856 ## - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="http://172.23.153.220/th.pdf">http://172.23.153.220/th.pdf</a>
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN)
Cataloger Amira
Reviser Cataloger
905 ## - LOCAL DATA ELEMENT E, LDE (RLIN)
Cataloger Nazla
Reviser Revisor
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme Dewey Decimal Classification
Koha item type Thesis
Holdings
Source of classification or shelving scheme Not for loan Home library Current library Date acquired Full call number Barcode Date last seen Koha item type Copy number
Dewey Decimal Classification   المكتبة المركزبة الجديدة - جامعة القاهرة قاعة الرسائل الجامعية - الدور الاول 11.02.2024 Cai01.10.15.Ph.D.2021.Ah.A 01010110083574000 22.09.2023 Thesis  
Dewey Decimal Classification   المكتبة المركزبة الجديدة - جامعة القاهرة مخـــزن الرســائل الجـــامعية - البدروم 11.02.2024 Cai01.10.15.Ph.D.2021.Ah.A 01020110083574000 22.09.2023 CD - Rom 83574.CD